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首页> 外文期刊>Paediatrics and international child health >An outbreak of dengue fever in children in the National Capital District of Papua New Guinea in 2016
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An outbreak of dengue fever in children in the National Capital District of Papua New Guinea in 2016

机译：2016年巴布亚新几内亚国家首都的儿童登革热爆发

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Background: The first documented outbreak of dengue which included cases with haemorrhage occurred in Papua New Guinea in 2016. Aim: To document the presentation and outcome of children with dengue in Port Moresby. Methods: This prospective cross-sectional descriptive study was conducted in Port Moresby General Hospital during a 6-month period from 6 January to 6 July 2016. Altogether, 165 children aged 1-14 years who met the WHO criteria for probable dengue were assessed and treated. Clinical features, presence of warning signs and signs of severe dengue, date of onset, management and outcome were recorded. Blood specimens were collected for serological testing and full blood count. Results: The median age was 6 years (interquartile range 3-8). Eighty-eight (53%) children had no warning signs and were managed as outpatients. Of the 165 patients, 42 (25%) had abdominal pain, 28 (17%) had bleeding and 3 (2%) had clinical evidence of fluid accumulation. The median (IQR) lowest platelet count in those tested was 34 x 10(9)/L (22-54). Two children were transfused with packed red blood cells and one received a platelet transfusion. No child developed dengue shock and none died. Non-structural protein 1 (NS1) and dengue IgM were positive in 122/144 (85%) and 36/111 (32%) of blood samples, respectively. 150/151 blood samples tested for dengue were positive on one or more tests. Conclusion: There is the potential for future outbreaks of increased severity in Papua New Guinea. Surveillance, mosquito reduction initiatives and health education programmes are needed to reduce the impact of future outbreaks.
机译：背景：2016年巴布亚新几内亚中患有血腥患者的首次记录爆发。目的：记录莫里斯比港登革热的儿童的介绍和结果。方法：该预期横断面描述研究在2016年1月6日至6日至6日至6日至6日的6个月内，在6个月的时间内在6个月内进行了6个月.114岁的165名符合人们达到谁的标准的165名儿童被评估，并进行了评估治疗。记录了临床特征，记录了警告标志，严重登革热，发病日期，管理和结果的迹象。收集血液标本用于血清学检测和全血。结果：中位年龄为6年（三分之一范围3-8）。八十八（53％）儿童没有警告标志，并作为门诊病人管理。在165名患者中，42例（25％）患有腹痛，28％（17％）出血，3（2％）有流体积累的临床证据。测试中的中位数（IQR）最低血小板计数为34×10（9）/ L（22-54）。两个孩子用包装的红细胞转染，一个接受血小板输血。没有孩子开发登革热休克，没有死亡。在122/144（85％）和36/111（32％）的血样中，非结构蛋白1（NS1）和登革热IgM分别为阳性。在一个或多个测试中测试了对登革热测试的150/151血液样品。结论：巴布亚新几内亚的严重程度增加了未来爆发的潜力。需要监测，需要蚊子减少举措和健康教育方案来减少未来爆发的影响。

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