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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >The Patient-Reported Outcomes Thermometer–5-Item Scale (5T-PROs): Validation of a New Tool for the Quick Assessment of Overall Health Status in Painful Rheumatic Diseases
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The Patient-Reported Outcomes Thermometer–5-Item Scale (5T-PROs): Validation of a New Tool for the Quick Assessment of Overall Health Status in Painful Rheumatic Diseases

机译：患者报告的结果温度计-5-项目规模（5T专利）：验证新工具，以便在痛苦的风湿病中快速评估整体健康状况

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Objective. To investigate the construct validity, reliability (internal consistency and retest reliability), and feasibility of the patient-reported outcomes thermometer–5-item scale (5T-PROs), a new tool to measure overall health status in patients with painful chronic rheumatic diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), axial spondyloarthritis (axialSpA), and fibromyalgia (FM). Methods. Consecutive patients have been involved in this study. The following analyses were performed to establish the validity of the 5T-PROs: (1) principal component factor analysis was used to identify the presence of a relatively small number of underlying latent factors than can be used to represent relations among sets of many variables; (2) Cronbach’s alpha was calculated as an indicator of internal consistency; and (3) Pearson product-moment correlations were conducted to assess the convergent validity. The 5T-PROs was also administered a second time (two weeks after the initial administration) to a subset of sample (n = 426) to allow for calculation of test-retest reliability. We used the intraclass correlation coefficient (ICC) as an estimate of test-retest reliability. Additionally, discriminant validity was tested using analysis of variance (ANOVA) with Bonferroni post hoc multiple comparisons, in different disease conditions. Feasibility was analyzed by the time taken in completing the 5T-PROs and the proportion of patients able to complete the 5 item. Results. 1,199 patients (572 with RA, 251 with axialSpA, 150 with PsA, and 226 with FM) were examined. The mean age was 55.7 (standard deviation: 13.1; range: 20 to 80) years. Factor analysis yielded two factors which accounted for 62.54% of the variance of the 5T-PROs. The first factor “Symptom Summary Score” (35.57% of the variance) revealed a good internal consistency (alpha = 0.88); the internal consistency of the second factor “Psychological Summary Score” (26.97% of the variance) was moderate (alpha = 0.69). The reliability of the whole instrument was good (alpha = 0.82). A very high correlation was obtained between Symptom Summary Score and SF-36 PCS and between pain thermometer intensity and SF-36 bodily pain. For all five items and summary scale scores of the SF-36, there was strong evidence that the mean rank of the scores differs significantly between the groups (Kruskal–Wallis tests, p<0.001). Discriminant validity, assessed by comparing the 5T-PRO dimensions in patients with different states of disease activity, showed that the 5T-PROs show moderate association with the presence of comorbidities. It was also noted that it was inversely correlated (p=0.01) to years of formal education. Conclusion. The 5T-PROs is easily administered, reliable and a valid instrument for evaluating the extensive multidimensional impact associated with chronic painful rheumatic conditions.
机译：客观的。探讨构建有效性，可靠性（内部一致性和重度可靠性），以及患者报告的结果的可行性，患者报告的结果温度计-5-项目规模（5T-PROS），一种测量患者患者患者患者的整体健康状况的新工具如类风湿性关节炎（RA），银屑病性关节炎（PSA），轴向脊椎细胞炎（轴向）和纤维肌痛（FM）。方法。连续患者参与了这项研究。进行以下分析以确定5T - 优点的有效性：（1）主要成分因子分析用于识别相对较少数量的潜在因子的存在，而不是用于代表许多变量集之间的关系; （2）Cronbach的alpha被计算为内部一致性的指标; （3）Pearson Product-Moregy相关性进行评估会聚有效性。 5T-Prose也将第二次（初始施用后两周）施用于样品（n = 426）的子集，以允许计算测试 - 保持最可靠性。我们使用脑内相关系数（ICC）作为测试 - 保持性可靠性的估计。此外，在不同的疾病条件下使用与Bonferroni的差异（ANOVA）分析进行判别有效性，在不同的疾病条件下进行多种比较。通过完成5T专利的时间和能够完成5项的患者的比例来分析可行性。结果。检查了1,199名患者（用RA，251带Axialspa，150带PSA和226名，带有FM）。平均年龄为55.7（标准差：13.1;范围：20至80）年。因子分析产生了两个因素，占5T专业人士差异的62.54％。第一因素“症状摘要得分”（35.57％的方差）揭示了良好的内部一致性（alpha = 0.88）;第二个因素“心理摘要评分”的内部一致性（差异的26.97％）是中等的（alpha = 0.69）。整个仪器的可靠性好（alpha = 0.82）。在症状摘要得分和SF-36 PC之间以及疼痛温度计强度和SF-36身体疼痛之间获得了非常高的相关性。对于SF-36的所有五个项目和摘要比例分数，有很强的证据表明，在组之间的分数的平均等级有显着不同（Kruskal-Wallis测试，P <0.001）。通过比较不同疾病活动状态的患者5T-Pro尺寸来评估的判别有效性表明，5T-优点显示与合并症的存在中度联系。还有人指出，它与正规教育的多年来相反（p = 0.01）。结论。 5T专业人员易于管理，可靠和有效的仪器，用于评估与慢性痛苦的风湿条件相关的广泛的多维影响。

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