...
首页> 外文期刊>Parasitology >Molecular characterization of Cystoisospora belli and unizoite tissue cyst in patients with Acquired Immunodeficiency Syndrome.
【24h】

Molecular characterization of Cystoisospora belli and unizoite tissue cyst in patients with Acquired Immunodeficiency Syndrome.

机译:患有免疫缺陷综合征患者膀胱孢子孢子贝利和Unizoite组织囊肿的分子表征。

获取原文
获取原文并翻译 | 示例
           

摘要

Cystoisospora belli is a coccidian protozoan that can cause chronic diarrhoea, acalculous cholecystitis and cholangiopathy in AIDS patients. We applied molecular methods to identify Cystoisospora at species level in AIDS patients presenting with and without the presence of unizoites in lamina propria. Coprological and histological analyses were performed in stool and/or biopsy samples from 8 Cystoisospora-infected patients. DNA from the same samples was used to amplify 2 fragments of the SSU-rRNA gene and the ITS-1 region. Sequencing of the resulting amplicons identified C. belli infections in all cases, independent of the presence or absence of unizoite tissue cysts. Further work should be considered in order to find molecular targets related to strain variations in C. belli.
机译:CystoisoSpora Belli是一种助性原生动物,可引起慢性腹泻,艾滋病患者的慢性胆囊炎和胆管病。 我们应用分子方法在艾滋病患者患者中鉴定在艾滋病患者的物种水平上,在没有外阴瘟疫的情况下鉴定艾滋病患者的艾滋病患者。 在8个半胱氨酸感染患者的粪便和/或活检样品中进行共性和组织学分析。 来自同一样品的DNA用于扩增SSU-RRNA基因的2片段和其-1区。 所得扩增子的测序在所有情况下鉴定了C.Belli感染,与未存在或不存在无渗组织囊肿无关。 应考虑进一步的工作,以便找到与C.Belli的菌株变化有关的分子靶标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号