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首页> 外文期刊>Parasitology >Diagnosis of human fascioliasis by stool and blood techniques: update for the present global scenario.
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Diagnosis of human fascioliasis by stool and blood techniques: update for the present global scenario.

机译：粪便和血液技术诊断人体粘性病毒：目前的全球情景更新。

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摘要

Before the 1990s, human fascioliasis diagnosis focused on individual patients in hospitals or health centres. Case reports were mainly from developed countries and usually concerned isolated human infection in animal endemic areas. From the mid-1990s onwards, due to the progressive description of human endemic areas and human infection reports in developing countries, but also new knowledge on clinical manifestations and pathology, new situations, hitherto neglected, entered in the global scenario. Human fascioliasis has proved to be pronouncedly more heterogeneous than previously thought, including different transmission patterns and epidemiological situations. Stool and blood techniques, the main tools for diagnosis in humans, have been improved for both patient and survey diagnosis. Present availabilities for human diagnosis are reviewed focusing on advantages and weaknesses, sample management, egg differentiation, qualitative and quantitative diagnosis, antibody and antigen detection, post-treatment monitoring and post-control surveillance. Main conclusions refer to the pronounced difficulties of diagnosing fascioliasis in humans given the different infection phases and parasite migration capacities, clinical heterogeneity, immunological complexity, different epidemiological situations and transmission patterns, the lack of a diagnostic technique covering all needs and situations, and the advisability for a combined use of different techniques, at least including a stool technique and a blood technique.
机译：在20世纪90年代之前，人类粘性病变诊断专注于医院或医疗中心的个体患者。案例报告主要来自发达国家，通常涉及在动物流行区域中分离的人类感染。从20世纪90年代中期开始，由于发展中国家的人类流行地区和人类感染报告的进步描述，而且对临床表现和病理学的新知识，在全球情景中进入了迄今为止的临床表现和病理学，新的情况。已证明人体粘性病如前所述，包括不同的传输模式和流行病学情况。粪便和血液技术，对人类诊断的主要工具，对患者和调查诊断都得到了改善。对人类诊断的目前可用性综合，重点是优缺点，样品管理，鸡蛋分化，定性和定量诊断，抗体和抗原检测，治疗后监测和控制后监测。主要结论是指鉴于不同的感染阶段和寄生虫迁移能力，临床异质性，免疫复杂性，不同流行病学情况和传输模式，缺乏涵盖所有需求和情况的诊断技术以及涵盖所有需求和情况的诊断技术以及可取性的诊断技术的明显困难为了结合不同技术，至少包括粪便技术和血液技术。

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