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首页> 外文期刊>Parasitology >Diagnosis of human fascioliasis by stool and blood techniques: update for the present global scenario.
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Diagnosis of human fascioliasis by stool and blood techniques: update for the present global scenario.

机译：通过粪便和血液技术诊断人筋膜炎：针对当前全球情况的更新。

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Before the 1990s, human fascioliasis diagnosis focused on individual patients in hospitals or health centres. Case reports were mainly from developed countries and usually concerned isolated human infection in animal endemic areas. From the mid-1990s onwards, due to the progressive description of human endemic areas and human infection reports in developing countries, but also new knowledge on clinical manifestations and pathology, new situations, hitherto neglected, entered in the global scenario. Human fascioliasis has proved to be pronouncedly more heterogeneous than previously thought, including different transmission patterns and epidemiological situations. Stool and blood techniques, the main tools for diagnosis in humans, have been improved for both patient and survey diagnosis. Present availabilities for human diagnosis are reviewed focusing on advantages and weaknesses, sample management, egg differentiation, qualitative and quantitative diagnosis, antibody and antigen detection, post-treatment monitoring and post-control surveillance. Main conclusions refer to the pronounced difficulties of diagnosing fascioliasis in humans given the different infection phases and parasite migration capacities, clinical heterogeneity, immunological complexity, different epidemiological situations and transmission patterns, the lack of a diagnostic technique covering all needs and situations, and the advisability for a combined use of different techniques, at least including a stool technique and a blood technique.
机译：在1990年代之前，人体筋膜病的诊断主要针对医院或保健中心的个别患者。病例报告主要来自发达国家，通常涉及动物流行地区孤立的人类感染。从1990年代中期开始，由于对发展中国家人类流行病地区和人类感染报告的描述不断增多，而且关于临床表现和病理学的新知识，迄今被忽视的新情况也进入了全球形势。事实证明，人类筋膜病比以前认为的更为明显，包括不同的传播方式和流行病学情况。凳子和血液技术是人类诊断的主要工具，已经针对患者和调查诊断进行了改进。综述了目前人类诊断的可用性，重点是优缺点，样品管理，卵分化，定性和定量诊断，抗体和抗原检测，治疗后监测和控制后监测。主要结论是，鉴于不同的感染阶段和寄生虫迁移能力，临床异质性，免疫学复杂性，流行病学情况和传播方式不同，缺乏涵盖所有需求和情况的诊断技术以及可取性，在人中诊断筋膜炎的明显困难结合使用不同的技术，至少包括粪便技术和血液技术。

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