Palaeoparasitology and palaeogenetics: review and perspectives for the study of ancient human parasites

NATHALIE M.-L.C?Té; MATTHIEULE BAILLY

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Palaeoparasitology and palaeogenetics: review and perspectives for the study of ancient human parasites

机译：猴酶学和古生病学：古代人寄生虫研究的审查与观点

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While some species of parasites can be identified to species level from archaeological remains using microscopy (i.e. Enterobius vermicularis, Clonorchis sinensis), others can only be identified to family or genus level as different species produce eggs with similar morphology (i.e. T?nia sp. and Echinococcus sp.). Molecular and immunological approaches offer the possibility to provide more precise determination at the species level. They can also identify taxa when classic parasite markers such as eggs or cysts have been destroyed over time. However, biomolecules can be poorly preserved and modern reference DNA is available only for a limited number of species of parasites, leading to the conclusion that classic microscopic observation should be combined with molecular analyses. Here we present a review of the molecular approaches used over the past two decades to identify human pathogenic helminths (Ascaris sp., Trichuris sp., E. vermicularis, Fasciola sp. etc.) or protists (Giardia sp., Trypanosoma sp., Leishmania sp. etc.). We also discuss the prospects for studying the evolution of parasites with genetics and genomics.

机译：虽然某些物种寄生虫可以从考古学遗骸鉴定到物种水平，但是使用显微镜（即Enterobius vermicularis，Clonorchis Sinensis），而其他物种只能被鉴定为不同物种产生具有相似形态的卵（即NIA SP。和echinococccus sp。）。分子和免疫学方法提供了在物种水平下提供更精确的测定。当鸡蛋或囊肿等经典寄生虫标记被随着时间的推移被破坏时，它们也可以识别出征。然而，生物分子可以保持不良，并且现代参考DNA仅适用于有限数量的寄生虫，导致经典微观观察应与分子分析结合的结论。在这里，我们介绍了过去二十年中使用的分子方法以鉴定人类病原蠕虫（Ascaris SP。，Trichuris Sp.，E.Vercularis，Fasciola Sp。等）或原始（Giardia sp.，Typanosoma sp。， Leishmania sp。）。）。我们还讨论了研究寄生虫遗传学和基因组学的进化的前景。

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《Parasitology》 |2018年第5期|共9页
作者
NATHALIE M.-L.C?Té; MATTHIEULE BAILLY;
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作者单位

University of Bourgogne Franche-Comte CNRS UMR 6249 Chrono-environment;

University of Bourgogne Franche-Comte CNRS UMR 6249 Chrono-environment;

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原文格式 PDF
正文语种 eng
中图分类寄生虫病;
关键词
Palaeoparasitology; palaeogenetics; helminth; protist; microscopy; PCR; next-generation sequencing;

机译：猴参之下;猴头生学学;蠕虫;质量;显微镜;PCR;下一代测序;

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1. Palaeoparasitology and palaeogenetics: review and perspectives for the study of ancient human parasites [J] . NATHALIE M.-L.C?Té, MATTHIEULE BAILLY Parasitology . 2018,第5期

机译：猴酶学和古生病学：古代人寄生虫研究的审查与观点
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Palaeoparasitology and palaeogenetics: review and perspectives for the study of ancient human parasites

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