...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Parasitology >Barcoding hybrids: heterogeneous distribution of Schistosoma haematobium × Schistosoma bovis hybrids across the Senegal River Basin
【24h】

Barcoding hybrids: heterogeneous distribution of Schistosoma haematobium × Schistosoma bovis hybrids across the Senegal River Basin

机译：条形码杂交种：塞内加尔河流域血吸虫血症血吸虫杂交种的异质分布

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Hybridization events between Schistosoma species (Digenea, Platyhelminthes) are reported with increasing frequency, largely due to improved access to molecular tools. Nevertheless, little is known about the distribution and frequency of hybrid schistosomes in nature. Screening for hybrids on a large scale is complicated by the need for nuclear and mitochondrial sequence information, precluding a ‘simple’ barcoding approach. Here we aimed to determine and understand the spatiotemporal distribution of Schistosoma haematobium × Schistosoma bovis hybrids in the Senegal River Basin. From ten villages, distributed over the four main water basins, we genotyped a total of 1236 schistosome larvae collected from human urine samples using a partial mitochondrial cox1 fragment; a subset of 268 parasites was also genotyped using ITS rDNA. Hybrid schistosomes were unevenly distributed, with substantially higher numbers in villages bordering Lac de Guiers than in villages from the Lampsar River and the Middle Valley of the Senegal River. The frequency of hybrids per village was not linked with the prevalence of urinary schistosomiasis in that village. However, we did find a significant positive association between the frequency of hybrids per village and the prevalence of Schistosoma mansoni. We discuss the potential consequences of adopting a barcoding approach when studying hybrids in nature.
机译：报告血吸瘤物种（Digenea，Platyhelminthes）之间的杂交事件随着频率的增加，很大程度上是由于改善了对分子工具的进入。然而，关于杂交血吸虫本质上的分布和频率知之甚少。对于大规模的杂交种筛选是对核和线粒体序列信息的需要复杂化，妨碍了“简单”的条形码方法。在这里，我们旨在确定和理解塞内加尔河流域血吸虫血症血吸虫杂交种的时空分布。从十个村庄分布在四个主要的水盆中，我们使用部分线粒体COX1片段从人类尿液中的1236个血吸虫幼虫进行了基因分为436阶段;使用其RDNA还基因分型268个寄生虫的子集。杂交血吸虫分布不均，在村庄边界德国的村庄中具有大幅增加的数量，而不是在灯柱河流和塞内加尔河中谷的村庄。每个村庄的杂种频率与那个村庄中的尿血吸虫病的患病率无关。然而，我们确实在每村杂交频率与血吸虫曼逊普遍存在之间找到了显着的积极关系。我们讨论了在本质上研究杂交种时采用条形码方法的潜在后果。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号