...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Parasitology >Lipid metabolism in Giardia: a post-genomic perspective.
【24h】

Lipid metabolism in Giardia: a post-genomic perspective.

机译：吉亚迪亚的脂质代谢：后基因组视角。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Giardia lamblia, a protozoan parasite, infects a wide variety of vertebrates, including humans. Studies indicate that this anaerobic protist possesses a limited ability to synthesize lipid molecules de novo and depends on supplies from its environment for growth and differentiation. It has been suggested that most lipids and fatty acids are taken up by endocytic and non-endocytic pathways and are used by Giardia for energy production and membrane/organelle biosynthesis. The purpose of this article is to provide an update on recent progress in the field of lipid research of this parasite and the validation of lipid metabolic pathways through recent genomic information. Based on current cellular, biochemical and genomic data, a comprehensive pathway has been proposed to facilitate our understanding of lipid and fatty acid metabolism/syntheses in this waterborne pathogen. We envision that the current review will be helpful in identifying targets from the pathways that could be used to design novel therapies to control giardiasis and related diseases.
机译：Giardia Lamblia是一种原生动物寄生虫，感染了各种各样的脊椎动物，包括人类。研究表明，这种厌氧物质师具有合成脂质分子De Novo的有限能力，并取决于其环境生长和分化的供应。已经提出，大多数脂质和脂肪酸被内吞和非内肾性途径占据，并且由Giardia用于能量产生和膜/细胞器生物合成。本文的目的是提供关于这种寄生虫的脂质研究领域的最新进展以及通过最近的基因组信息验证脂质代谢途径的验证。基于目前的细胞，生物化学和基因组数据，已经提出了一种综合途径，以促进我们对该水性病原体中脂质和脂肪酸代谢/合成的理解。我们设想，目前的审查将有助于识别可用于设计新疗法以控制胃肠病和相关疾病的途径的目标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号