...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BJOG: an international journal of obstetrics and gynaecology >Comparative study of the effects of a progestogen-only pill containing desogestrel and an intrauterine contraceptive device in lactating women.
【24h】

Comparative study of the effects of a progestogen-only pill containing desogestrel and an intrauterine contraceptive device in lactating women.

机译：含去氧孕烯和宫内避孕器的仅孕激素药丸对哺乳期妇女的比较研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To evaluate the effects of desogestrel 75 microg/day, as a progestogen-only pill compared with a copper-bearing intrauterine contraceptive device (IUCD) on lactation and to study the safety of both treatments in mothers and children. Transfer of etonogestrel to breast milk was studied in a subgroup of desogestrel users. The children were to be followed up until 2.5 years of age. DESIGN: An open, non-randomised, group-comparative study in lactating women. SETTING: University Hospital, Reykjavik, Iceland. PARTICIPANTS: A total of 83 lactating women; 42 received desogestrel and 41 had an IUCD inserted for seven consecutive treatment cycles of 28 days. METHODS: Evaluation visits were planned at baseline and at the end of treatment cycles 1, 4 and 7. The amount of breast milk was determined by weighing the infants before and after feeding, at baseline and after treatment cycles I and 4. Milk samples were obtained at the same time for constituent measurements. Safety was studied by structured medical examinations and by recording adverse experiences in mothers and children. RESULTS: There were no significant differences between the desogestrel and IUCD groups in composition and quantity of breast milk nor in growth and development of the children followed up to the age of 2.5 years. In the desogestrel group a slightly higher incidence of mild adverse experiences of a hormonal nature was reported among both mothers and infants. Of the children 82% were followed until 1.5 years of age and 50% until 2.5 years. CONCLUSION: The use of desogestrel 75 microg/day did not change the amount and composition of breast milk nor did it affect growth and development of the breastfed children. It appears to be a safe and effective contraceptive method for lactating women
机译：目的：评估作为口服仅孕激素的避孕药与含铜子宫内避孕器（IUCD）相比，地索孕酮75微克/天的泌乳效果，并研究这两种疗法对母亲和儿童的安全性。在一个去甲孕酮使用者的亚组中研究了依托孕酮向母乳的转移。对儿童进行随访直至2.5岁。设计：一项针对哺乳期妇女的开放，非随机，小组比较的研究。地点：冰岛雷克雅未克大学医院。参加者：共有83名哺乳期妇女。 42例接受去氧孕烯，41例接受IUCD，连续七个治疗周期为28天。方法：计划在基线时以及治疗周期1、4和7结束时进行评估访问。母乳量通过在喂养前后，在基线I和4和治疗周期4之后对婴儿进行称重来确定。同时获得的用于成分测量。通过结构性医学检查并记录母亲和儿童的不良经历来研究安全性。结果：去氧孕烯和IUCD组之间的母乳成分和数量以及2.5岁以下儿童的生长发育都没有显着差异。在去氧孕烯组中，据报道母亲和婴儿的激素性轻度不良反应发生率略高。在这些儿童中，有82％的儿童被跟踪到1.5岁，而50％的儿童被跟踪到2.5岁。结论：每天使用75微克的去氧孕烯既没有改变母乳的含量和成分，也没有影响母乳喂养儿童的生长发育。这似乎是哺乳期妇女的一种安全有效的避孕方法

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号