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首页> 外文期刊>Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies >Prevalence of Acute Neurologic Insults: A Case for Going Global
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Prevalence of Acute Neurologic Insults: A Case for Going Global

机译：急性神经系统侮辱的患病率：全球化的案例

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Among organ system dysfunction, neurologic dysfunction possibly has the most visible and far reaching impact on the child, the family and the society. Childhood neurodisability from acute insults can translate into years of lost human potential and a challenged life. To plan the strategies to reduce the burden of neurodisability secondary to acute neurologic insults, an estimate of the current burden of the insults collected from diverse settings across the world is needed. Such data can guide resource allocation, policy making, and further research. A previous retrospective cohort study from the United States reported on data from 273,900 admissions of children with neurologic diagnoses. The most common diagnoses were seizures (53.9%) and traumatic brain injury (17.3%). Several notable facts that emerged from this study were: children with neurologic diagnoses had nearly three times greater ICU use than other hospitalized children, accounted for nearly half of deaths, and had more than three times the mortality of other patients. Children with neurologic diagnoses also had a significantly longer median hospital length of stay than other children and greater median hospital costs. Although the data from above referred study are very large, it is representative of only one country. For generating broadly representative epidemiological data on acute neurologic insults, there is a need for global multiregion data. The Prevalence of Acute critical Neurological disease in children: a Global Epidemiological Assessment (PANGEA) study is a worthwhile attempt to address this need. In this international study, preliminary data from academic and resource-rich settings give initial estimates of nature of primary neurologic insults in children admitted to the PICUs. It is a well-executed example of an international collaborative epidemiological research study.
机译：在器官系统功能障碍中，神经系统功能障碍可能是对孩子，家庭和社会最明显和最伸展的影响。急性侮辱的儿童神经性能力可以转化为人类潜力的多年和挑战的生活。为了规划减少急性神经系统侮辱的神经炎性的负担的策略，需要估计来自世界各地的各种环境所收集的侮辱的负担。此类数据可以指导资源分配，策略制作和进一步研究。从美国的先前回顾性队列研究报告了来自患有神经系统诊断的儿童的273,900人。最常见的诊断是癫痫发作（53.9％）和创伤性脑损伤（17.3％）。从本研究中出现的几个值得注意的事实是：具有神经系统诊断的儿童比其他住院儿童更大的ICU使用近三倍，占近一半的死亡，并且具有其他患者的死亡率的三倍以上。具有神经系统诊断的儿童也比其他儿童和更高的医院成本更长的医院住宿时间明显更长。虽然来自上述研究的数据非常大，但它仅是一个国家的代表。为了产生关于急性神经系统损伤的广泛代表性流行病学数据，需要全球多限内容数据。儿童急性关键神经疾病的患病率：全球流行病学评估（Pangea）研究是一种值得解决这种需求的尝试。在这项国际研究中，来自学术和资源丰富的环境的初步数据估计对帕皮斯录取的儿童的原发性神经系统侮辱性质估计。这是一个执行的国际协同流行病学研究研究的实例。

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