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Alopecia Areata: An Update on Treatment Options for Children

机译:Alopecia Areata:儿童治疗方案的更新

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摘要

Abstract Pediatric alopecia areata is a spectrum of autoimmune non-scarring alopecia in which some patients lose small patches of hair from their scalp but others lose more or all of the hair from the scalp and body, including eyebrows and eyelashes. Few studies have looked at therapies for this disorder in children, so much of the data are derived from adult literature and describe off-label use of medication. Generally, topical therapies consisting of topical steroids and topical irritating compounds/contact sensitizers are used. Systemic therapies that block the immune system, including Janus kinase (JAK) inhibitors, have also been used in this disease. This paper reviews the data on therapy for alopecia areata in pediatric patients.
机译:摘要小儿脱发AREATA是一种自身免疫性非疤痕的脱脂症,其中一些患者失去了从他们的头皮中失去了小的头发,但其他患者从头皮和身体中失去了更多或所有的头发,包括眉毛和睫毛。 少数研究已经看过儿童这种疾病的治疗,因此大部分数据来自成人文学,并描述了对药物的标签使用。 通常,使用由局部类固醇和局部刺激化合物/接触敏化剂组成的局部疗法。 在这种疾病中也已经使用了阻止免疫系统的系统性疗法,包括Janus激酶(Jak)抑制剂。 本文综述了儿科患者脱发治疗的数据。

著录项

  • 来源
    《Pediatric drugs》 |2017年第5期|共12页
  • 作者单位

    Georgetown University School of Medicine;

    The Children’s Hospital of Philadelphia and The University of Pennsylvania Perlman School of;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药学;
  • 关键词

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