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首页> 外文期刊>Pathobiology: journal of immunopathology, molecular and cellular biology >Pathology of the Fallopian Tube: Tubal Involvement by Ovarian Tumors and Incidental Findings in the Nontumoral Setting
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Pathology of the Fallopian Tube: Tubal Involvement by Ovarian Tumors and Incidental Findings in the Nontumoral Setting

机译：输卵管的病理学：卵巢肿瘤的输卵管涉及非笨重中的偶然发现

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摘要

The fallopian tube is thought to be the site of origin of most high-grade serous carcinomas (HGSCs). However, how often the tube is abnormal in the setting of other ovarian tumors is unknown. The aim of this study is to define the frequency of tubal abnormalities in the tumoral (n = 245) and nontumoral (n = 184) setting. We found that in ovarian tumors, 52.2% of the tubes were normal, while 39.2% were affected by the tumor. Abnormal tubes were found in 80% of HGSCs, in 21% of mucinous carcinomas, in 83.3% of seromucinous carcinomas, in 33.3% of endometrioid carcinomas, in 20% of clear-cell carcinomas, and in 10.5% of borderline tumors. Among normal tubes, almost 70% were histologically normal; transitional metaplasia was present in 17.4%, endometriosis in 8.1%, and adenofibroma in 2.2%, and 1.1% had an incidental serous intraepithelial tubal carcinoma. To conclude, the fallopian tube is abnormal in most serous carcinomas, and in a smaller number of endometrioid, clear-cell and mucinous carcinomas as well as borderline tumors. It is often abnormal in seromucinous tumors, but larger series are needed to study this rare subtype.
机译：输卵管被认为是大多数高级浆液癌（HGSC）的起源部位。然而，在其他卵巢肿瘤的设置中，管道异常的频率是未知的。本研究的目的是定义肿瘤（n = 245）和非笨重（n = 184）设置的管状异常的频率。我们发现，在卵巢肿瘤中，52.2％的管是正常的，而39.2％受到肿瘤的影响。在80％的HGSC中发现异常管，占粘液癌的21％，血清癌的83.3％，在33.3％的子宫内甲状腺癌中，含有澄清细胞癌的20％，以及10.5％的边缘肿瘤。在正常管中，近70％是组织学正常的;过渡性细胞增长率为17.4％，子宫内膜异位症8.1％，腺草瘤为2.2％，1.1％有偶然的浆液中性输卵管癌。为了得出结论，在大多是浆液癌中，输卵管是异常的，并且在较少数量的子宫内甲状腺体，透明细胞和粘液癌以及边缘肿瘤中。血清瘤肿瘤通常是异常的，但需要较大的系列来研究这种罕见的亚型。

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