Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus

Uniyal Ankit; Singh Raghunath; Akhtar Ansab; Bansal Yashika; Kuhad Anurag; Sah Sangeeta Pilkhwal

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Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus

机译：通过恢复皮质和海马的生理改变，对丙酮酮的双丙酰胺抢救缺陷缺乏创伤后应激障碍的实验范式缺陷

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Pharmacotherapy and cognitive behavioral therapy, both fail to treat post-traumatic stress disorder (PTSD) in a considerable number of populations. The persistence of traumatic memories and deficit in extinction contributes to the failure of exposure therapy in PTSD.

机译：药物疗法和认知行为治疗，两者都未能在相当多的人群中治疗创伤后应激障碍（PTSD）。创伤记忆和缺陷缺陷的持续存在促进了接触者治疗的失败。

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来源
《Pharmacology, Biochemistry and Behavior》 |2019年第2019期|共15页
作者
Uniyal Ankit; Singh Raghunath; Akhtar Ansab; Bansal Yashika; Kuhad Anurag; Sah Sangeeta Pilkhwal;
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Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

Panjab Univ Univ Inst Pharmaceut Sci Pharmacol Div UGC CAS Chandigarh 160014 India;

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正文语种 eng
中图分类药理学;
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1. Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus [J] . Uniyal Ankit, Singh Raghunath, Akhtar Ansab, Pharmacology, Biochemistry and Behavior . 2019,第期

机译：通过恢复皮质和海马的生理改变，对丙酮酮的双丙酰胺抢救缺陷缺乏创伤后应激障碍的实验范式缺陷
2. Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder. [J] . Bremner JD, Vermetten E, Schmahl C, Psychological medicine . 2005,第6期

机译：正电子发射断层扫描成像技术与儿童性虐待相关的创伤后应激障碍的恐惧获取和消灭范例的神经相关。
3. Self-Stimulation Rewarding Experience Restores Stress-Induced CA3 Dendritic Atrophy, Spatial Memory Deficits and Alterations in the Levels of Neurotransmitters in the Hippocampus [J] . K. Ramkumar, B. N. Srikumar, B. S. Shankaranarayana Rao, Neurochemical Research . 2008,第9期

机译：自我刺激的奖励经验可恢复应激诱导的CA3树突萎缩，空间记忆障碍和海马神经递质水平的改变
4. Perfusion Deficits and Functional Connectivity Alterations in Patients with Post-Traumatic Stress Disorder [C] . Yang Liu, Baojuan Li, Xi Zhang, Conference on biomedical applications in molecular, structural, and functional imaging . 2016

机译：创伤后应激障碍患者的血流灌注不足和功能连接改变
5. Behavioral, biochemical, and physiological components of stress-enhanced fear learning in an animal model of post-traumatic stress disorder. [D] . Meyer, Edward. 2014

机译：创伤后应激障碍动物模型中应激增强恐惧学习的行为，生化和生理成分。
6. Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder [O] . J. DOUGLAS BREMNER, ERIC VERMETTEN, CHRISTIAN SCHMAHL, -1

机译：与儿童性虐待相关的创伤后应激障碍妇女的恐惧获取和消灭范例的神经相关的正电子发射断层成像
7. Predator exposure/psychosocial stress animal model of post-traumatic stress disorder modulates neurotransmitters in the rat hippocampus and prefrontal cortex. [O] . C Brad Wilson, Philip J Ebenezer, Leslie D McLaughlin, 2014

机译：捕食者暴露/心理社会应激动物模型的创伤后应激障碍调节大鼠海马和前额叶皮质中的神经递质。
8. Conditioned Fear Extinction and Generalization in Post-Traumatic Stress Disorder. [R] . Norrholm, S. D., Duncan, E., Ressler, K., 2012

机译：创伤后应激障碍的条件性恐惧灭绝与泛化。

Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus

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