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首页> 外文期刊>BJU international >Laparoscopic augmentation cystoplasty: a comparison between native ileum and small intestinal submucosa in the porcine model.
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Laparoscopic augmentation cystoplasty: a comparison between native ileum and small intestinal submucosa in the porcine model.

机译：腹腔镜增强膀胱成形术：猪模型中自然回肠和小肠粘膜下层的比较。

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摘要

OBJECTIVES: To determine the feasibility of laparoscopic augmentation cystoplasty (LAC) in the porcine model and to compare LAC using standard bowel vs a small intestinal submucosa (SIS) allograft. MATERIALS AND METHODS: Fourteen female pigs underwent LAC; six had standard ileal AC and eight AC with SIS. All the pigs had limited cystometrogram studies before surgery to determine bladder capacity. At 6 weeks after surgery the pigs were anaesthetized, the bladder capacities were re-assessed and then the pigs were killed; the bladders were harvested and examined histologically. RESULTS: In all, 12 of 14 pigs completed the 6-week survival period; two pigs from the SIS group died from urinary ascites secondary to anastomotic leaks at the cystoplasty site. There were no complications in the ileal augmentation group. The operative duration was similar in both groups. The bladder capacities increased significantly in both groups, although more reliably in the native ileum group. In two pigs in the SIS group there was no increase in bladder capacity. CONCLUSIONS: LAC is feasible in the porcine model and results in a significant increase in bladder capacity. AC using SIS does not appear to increase bladder capacity as reliably as native ileum, and has a higher complication rate.
机译：目的：确定在猪模型中进行腹腔镜增强膀胱成形术（LAC）的可行性，并比较同种异体小肠粘膜下皮（SIS）与标准肠移植的LAC。材料与方法：14只雌性猪进行了LAC。 6个使用标准回肠AC，8个使用SIS。所有猪在手术前均进行了有限的膀胱造影检查研究，以确定膀胱容量。手术后第6周，对猪进行麻醉，重新评估膀胱容量，然后将猪处死。收集膀胱并进行组织学检查。结果：总共有14头猪中的12头完成了6周的生存期。 SIS组的两只猪死于膀胱成形术部位因吻合口漏继发的尿腹水。回肠扩大组没有并发症。两组的手术时间相似。两组的膀胱容量均显着增加，尽管在自然回肠组中更可靠。 SIS组的两只猪的膀胱容量没有增加。结论：LAC在猪模型中是可行的，并导致膀胱容量的显着增加。使用SIS的AC似乎不像自然回肠一样可靠地增加膀胱容量，并且具有更高的并发症发生率。

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