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The role of eukaryotic initiation factor 3 in plant translation regulation

机译：真核激发因子3在植物翻译调节中的作用

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Regulation of translation represents a critical step in the regulation of gene expression. In plants, the translation regulation plays an important role at all stages of development and, during stress responses, functions as a fast and flexible tool which not only modulates the global translation rate but also controls the production of specific proteins. Regulation of translation is mostly focused on the initiation phase. There, one of essential initiation factors is the large multisubunit protein complex of eukaryotic translation initiation factor 3 (eIF3). In all eukaryotes, the general eIF3 function is to scaffold the formation of the translation initiation complex and to enhance the accuracy of scanning mechanism for start codon selection. Over the past decades, additional eIF3 functions were described as necessary for development in various eukaryotic organisms, including plants. The importance of the eIF3 complex lies not only at the global level of initiation event, but also in the precise translation regulation of specific transcripts. This review gathers the available information on functions of the plant eIF3 complex.
机译：翻译调节代表了基因表达调控的关键步骤。在植物中，翻译规则在开发的所有阶段起着重要作用，并且在压力响应期间，用作快速和灵活的工具，不仅调节全球转换率，而且还控制了特定蛋白质的产生。翻译的调节主要集中在起始阶段。在那里，一个基本的启动因子是真核翻译引发因子3（EIF3）的大型多管蛋白复合物。在所有真核生物中，通用EIF3功能是脚手架形成翻译启动复合体，并提高起始密码子选择的扫描机制的准确性。在过去的几十年中，额外的EIF3功能被描述为各种真核生物的开发所必需的，包括植物。 EIF3复合体的重要性不仅在于全球启动事件层面，而且在特定转录物的精确翻译调节中。此审查收集了有关工厂EIF3复合物功能的可用信息。

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