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首页> 外文期刊>Polymer Composites >Hydrophilically modified poly(vinylidene fluoride) nanofibers incorporating cellulose acetate fabricated by colloidal electrospinning for future tissue-regeneration applications
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Hydrophilically modified poly(vinylidene fluoride) nanofibers incorporating cellulose acetate fabricated by colloidal electrospinning for future tissue-regeneration applications

机译：亲水性改性的聚（偏二氟乙烯）纳米纤维，其含有胶体静电纺丝制备的醋酸纤维素，用于未来的组织再生应用

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摘要

A composite consisting of mechanically strong Poly(vinylidene fluoride) (PVDF) and biochemically favorable Cellulose acetate (CA) nanofibers can be considered as an excellent choice due to their excellent mechanical properties of PVDF and desirable biological properties of CA. However, preparing nanofibers of composites, involving CA requires the use of harsh acidic solutions and high temperatures, which can have serious consequences on a bio-aspect of CA. In this study, we have successfully prepared suitable solutions comprising of PVDF and CA in dimethylformamide. Subsequently, these solutions were directly ejected out as nanofibers during the process of electrospinning. The nanofibers synthesized were characterized for physicochemical properties by scanning electron microscopy, contact angle, Fourier transform infrared, thermogravimetric, and X-ray diffraction spectroscopy. The results revealed that CA can be easily introduced in PVDF nanofibers, using a single solvent (i.e., dimethylformamide). The introduced strategy can favorably preserve the inherent biological nature of CA. Moreover, the nanofibers prepared using this methodology was investigated for cell toxicity and cell attachment properties. These studies were carried to figure out the beneficial features shown by the CA to suppress inherent toxicity of PVDF nanofibers. The results of these studies proved that NIH 3T3 fibroblasts upon incubation in the presence of composite nanofibers containing CA can proliferate well when compared to pristine PVDF nanofibers. POLYM. COMPOS., 40:1619-1630, 2019. (c) 2018 Society of Plastics Engineers
机译：一种由机械强的聚（偏二氟乙烯）（PVDF）和生物化有利纤维素乙酸醋酸纤维素（CA）纳米纤维组成的复合材料可被认为是由于它们的PVDF和CA的理想生物学性能优异的机械性能而成为优异的选择。然而，制备复合材料的纳米纤维，涉及CA需要使用苛性酸性溶液和高温，这可能对CA的生物方面具有严重后果。在该研究中，我们已经成功地制备了在二甲基甲酰胺中包含PVDF和Ca的合适溶液。随后，在静电纺丝过程中，将这些溶液直接作为纳米纤维喷出。合成的纳米纤维通过扫描电子显微镜，接触角，傅里叶变换红外，热重分析和X射线衍射光谱，表征了物理化学性质的特征。结果表明，使用单个溶剂（即二甲基甲酰胺），可以在PVDF纳米纤维中容易地引入CA。引入的策略可以有利地保护CA的固有生物学。此外，研究了使用该方法制备的纳米纤维用于细胞毒性和细胞附着性能。携带这些研究以弄清楚CA所示的有益特征，以抑制PVDF纳米纤维的固有毒性。这些研究的结果证明，与原始PVDF纳米纤维相比，含有Ca的复合纳米纤维的复合纳米纤维的存在时，NIH 3T3成纤维细胞在含有CA的存在中的孵育。聚合物。 Compos。，40：1619-1630,2019。（c）2018年塑料工程师协会

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  • 来源
    《Polymer Composites》 |2019年第4期|共12页
  • 作者

    Sheikh Faheem A.; Beigh Mushtaq A.; Qadir Abdul S.; Qureshi Shabir H.; Kim Hern;

  • 作者单位

    Univ Kashmir Dept Nanotechnol Srinagar 190006 Jammu &

    Kashmir India;

    Univ Kashmir Dept Nanotechnol Srinagar 190006 Jammu &

    Kashmir India;

    Northwestern Univ Div Hematol Oncol Feinberg Sch Med Chicago IL 60611 USA;

    St Louis Univ Sch Med Dept Biochem &

    Mol Biol St Louis MO 63104 USA;

    Myongji Univ Dept Energy Sci &

    Technol Energy &

    Environm Fus Technol Ctr Yongin 17058 Kyonggi Do South Korea;

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  • 正文语种 eng
  • 中图分类 增强塑料、填充塑料;
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