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Preparation and properties of a biodegradable inferior vena cava filter

机译:可生物降解的下腔静脉过滤器的制备及性能

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>In this study, a new type of biodegradable inferior vena cava filter was designed and prepared based on polylactic acid. In addition to having the main functions of a common filter, it is also completely biodegradable in the human body without secondary surgical removal. The changes of surface morphology, molecular weight, viscosity, and radial support strength with degradation time were systematically investigated via degradation experiments in vitro. The results of crimping and expansion tests of the filter showed that reducing the crimping time and increasing the release time make it easier for the filter to recover to its original diameter. Further, the results of a thrombus capture experiment in vitro showed that the thrombus filtration ratio for the filter with double‐layer connection structure is 90%.
机译: 在该研究中,基于聚乳酸设计并制备了一种新型的可生物降解的下腔静脉过滤器。 除了具有常见过滤器的主要功能之外,在人体中也完全可生物降解,而无过外科手术。 通过体外降解实验系统地研究了表面形态,分子量,粘度和径向支撑强度的变化,具有降解时间。 滤波器的压接和膨胀试验结果显示,减小压接时间并增加释放时间使得过滤器更容易恢复到其原始直径。 此外,体外血栓捕获实验的结果表明,具有双层连接结构的过滤器的血栓过滤比为90%。

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