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首页> 外文期刊>Polymers for advanced technologies >Preparation of highly interconnected porous poly(ε‐caprolactone)/poly(lactic acid) scaffolds via supercritical foaming
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Preparation of highly interconnected porous poly(ε‐caprolactone)/poly(lactic acid) scaffolds via supercritical foaming

机译：通过超临界发泡制备高互连的多孔聚（ε-己内酯）/聚（乳酸）支架

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摘要

> Highly interconnected porous polymer scaffolds were prepared by gas foaming. Poly(ε‐caprolactone)/poly(lactic acid) blends were melt mixed and batch foamed using CO 2 as a physical blowing agent. The effects of the foaming temperature, pressure, and CO 2 saturation time on the foam morphology were related to the mechanical properties of the scaffolds. The cell size in cross section of scaffolds decreased and became more homogeneous until CO 2 saturation time reached 1.5?hours. With an increase in temperature, the cell size increased markedly and the cell size uniformity decreased gradually, whereas the reverse happened when the foaming pressure was increased. Meanwhile, many open cells can also be detected on the surface of scaffolds. High porosity and an open‐cell content of greater than 90% were obtained. The compressive strength of scaffolds was regulated by controlling the foam architecture. The information gathered in this study may provide a theoretical basis for research into porous tissue engineering scaffolds.
机译： > 通过气体发泡制备高度相互连接的多孔聚合物支架。聚（ε-己内酯）/聚（乳酸）共混物熔融混合和批量使用CO 2 作为物理吹药剂。发泡温度，压力和CO的影响 2 泡沫形态上的饱和时间与支架的机械性能有关。支架的横截面中的细胞尺寸降低，变得更加均匀，直到CO 2 饱和时间达到1.5？小时。随着温度的增加，电池尺寸明显增加，并且电池尺寸均匀性逐渐降低，而当发泡压力增加时发生反转。同时，也可以在支架的表面上检测到许多开放细胞。获得高孔隙率和开放细胞含量大于90％。通过控制泡沫结构来调节支架的抗压强度。本研究中收集的信息可以为研究多孔组织工程支架提供理论依据。

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  • 来源
    《Polymers for advanced technologies》 |2018年第12期|共10页
  • 作者

    Sun Shuhao; Li Qian; Zhao Na; Jiang Jing; Zhang Kangkang; Hou Jianhua; Wang Xiaofeng; Liu Guoji;

  • 作者单位

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Mechanics and Engineering ScienceZhengzhou University National Center for International Joint research of Micro‐Nano Molding TechnologyZhengzhou Henan China;

    School of Chemical Engineering and EnergyZhengzhou UniversityZhengzhou Henan China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 高分子化合物工业（高聚物工业）;
  • 关键词

    batch foaming; mechanical properties; poly(ε‐caprolactone)/poly(lactic acid); pore morphology; scaffold;

    机译：批量发泡;机械性能;聚（ε-己内酯）/聚（乳酸）;孔形态;脚手架;

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