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首页> 外文期刊>Plasmid: An International Journal Devoted to Extrachromosomal Gene Systems >Reconstitutions of plasmid partition systems and their mechanisms
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Reconstitutions of plasmid partition systems and their mechanisms

机译:质粒分区系统的重建及其机制

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Bacterial plasmid and chromosome segregation systems ensure that genetic material is efficiently transmitted to progeny cells. Cell-based studies have shed light on the dynamic nature and the molecular basis of plasmid partition systems. In vitro reconstitutions, on the other hand, have proved to be an invaluable tool for studying the minimal components required to elucidate the mechanism of DNA segregation. This allows us to gain insight into the biological and biophysical processes that enable bacterial cells to move and position DNA. Here, we review the reconstitutions of plasmid partition systems in cell-free reactions, and discuss recent work that has begun to challenge long standing models of DNA segregation in bacteria. (C) 2017 Elsevier Inc. All rights reserved.
机译:细菌质粒和染色体隔离系统确保遗传物质有效地传递给后代细胞。 基于细胞的研究对动态性质和质粒分配系统的分子基础进行了光。 另一方面,在体外重建中,已经证明是研究阐明DNA偏析机制所需的最小成分的宝贵工具。 这使我们能够深入了解生物和生物物理过程,使能细菌细胞移动和位置DNA。 在这里,我们审查了无细胞反应中质粒分区系统的重建,并讨论了最近开始挑战细菌中DNA偏析的长期模型的工作。 (c)2017年Elsevier Inc.保留所有权利。

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