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Hormonal contraception: total loss of libido

机译:荷尔蒙避孕:性质损失

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摘要

At the end of 2017, the World Health Organization (WHO) Pharmacovigilance Centre in Uppsala published an analysis of 694 reports of loss of libido ascribed to combined oestrogen-progestogen or progestogen-only hormonal contraceptives, recorded in its database (1). In 112 cases, a regression of the problems was noted on stopping the contraceptive and in 2 cases the problems reappeared after re-starting it. 77 of these reports were submitted by the users. They described a total loss of libido which affected their life and they had not been informed of a possible link with the hormonal contraceptive (1). The adverse effects most often quoted in association with loss of libido were: depression and mood change, headaches, weight gain and anxiety. Depression is a confounding factor in the assessment of loss of libido because it is itself a cause of reduced libido. Depression was cited in 245 out of 694 cases analysed and in 44 of the 112 cases it regressed on stopping the contraceptive. However, in a large number of cases there was no associated depression (1).
机译:截至2017年底,世界卫生组织(世卫组织)乌普萨拉的药物组织(Who)Pharmacovilece中心发表了694次归因于雌激素 - 孕激素或孕激素诱导症的性欲丧失的报告,其数据库(1)中记录的雌激素 - 孕激素或孕激素的避孕药。在112例案件中,在阻止避孕药中并在2例患者重新开始后出现的问题,注意到问题的回归。这些报告中的77名由用户提交。他们描述了影响其生命的性欲的总损失,并且没有被告知荷尔蒙避孕药(1)的可能链接。最常伴的不良反应与性欲丧失引用:抑郁和情绪变化,头痛,体重增加和焦虑。抑郁症是评估性欲丧失的混淆因素,因为它本身就是性欲减少的原因。在694例中分析的245例中引用了抑郁症,并在112例中的44例中,在停止避孕药中的112例中。但是,在大量情况下,没有相关的抑郁症(1)。

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    《Prescrire international》 |2018年第195期|共1页
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  • 正文语种 eng
  • 中图分类 药学;
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