INN Common stem -ciclovir

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INN Common stem -ciclovir

机译：Inn Common Stem -Ciclovir

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According to the nomenclature established by the World Health Organization (WHO) to devise international non-proprietary names (INNs), the INNs of bicyclic hetero-cyclic compounds with antiviral properties end in the common stem -ciclovir (1). Five drugs with this stem are marketed in France as of 28 August 2018, to treat various viral infections due to herpes viruses, varicella zoster virus or cytomegalo-virus (CMV): aciclovir, famciclovir, ganciclovir, vala-ciclovir and valganciclovir. More generally, the common stem -vir (or vir- or -vir-) was chosen by the WHO to denote antiviral drugs. Other stems containing -vir are used to denote specific types of antivirals within this group, for example: the INNs of RNA polymerase (NS5B) inhibitors, used to treat hepatitis C, end in the stem -buvir (e.g. sofosbuvir); and the INNs of HIV-protease inhibitors end in the stem -navir (e.g. lopinavir) (1). The INNs of a few antivirals are exceptions to this rule by lacking the common stem -vir, such as emtri-citabine, lamivudine, telbivudine and zidovudine, all used to treat HIV infection or hepatitis B.

机译：根据世界卫生组织（世卫组织）建立的命名法（世卫组织）制定了国际非专有名称（INNS），抗病毒性质在常见的茎中的抗病毒性质的局部杂环化合物（1）。截至2018年8月28日，该茎的五种毒品在法国销售，以治疗疱疹病毒，种子疱疹病毒或缩细胞病毒（CMV）：Aciclovir，Famciclovir，Ganciclovir，Vala-Ciclovir和Valganciclovir，治疗各种病毒感染。更一般地，由世卫组织选择常见的茎-VIR（或VIR-或-VIR-）来表示抗病毒药物。含有-VIR的其他茎用于表示该组内的特异性类型的抗病毒，例如：用于治疗丙型肝炎的RNA聚合酶（NS5B）抑制剂的局部，在茎-Buvir（例如Sofosbuvir）中结束;和艾滋病毒蛋白酶抑制剂的局限性 - 在茎 - 纳韦（例如Lopinavir）（1）中。少数抗病毒群岛的旅馆是缺乏普通茎 - vir的规则的例外，例如Emtri-citabine，拉米夫定，替哌丁和齐凡押，所有这些都用于治疗HIV感染或乙型肝炎。

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《Prescrire international》 |2019年第203期|共1页
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INN Common stem -ciclovir

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