tiotropium (Spiriva Respimat0) and severe asthma from six years of age

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tiotropium (Spiriva Respimat0) and severe asthma from six years of age

机译：Tiotropium（Spiriva Respimat0）和六岁的严重哮喘

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In children and adolescents, addition of inhaled tiotropium to long-term maintenance treatment of asthma improves lung function test results in the short term, but without demonstrated clinical benefit, and at the cost of antimuscarinic, and possibly cardiovascular, adverse effects. SPIRIVA RESPIMAT0 - tiotropium solution for inhalation, 2.5 microgram of tiotropium per delivered dose, bronchodilator; long-acting antimuscarinic, New indication: "add-on maintenance bronchodilator treatment in patients aged 6 years and older with severe asthma who experienced one or more severe asthma exacerbations in the previous year" and who are currently treated with an inhaled corticosteroid and at least one other maintenance treatment. [EU decentralised procedure]

机译：在儿童和青少年中，向哮喘的长期维护治疗添加吸入的噻托米，在短期内提高了肺功能测试结果，但没有表现出临床效益，并且以抗血清素的成本，并且可能心血管，不良反应。 Spiriva Respimat0 - 吸入的噻托溴铵解决方案，2.5微克毒素每递送剂量，支气管扩张剂; 长效的抗血清素，新症状：“6岁及以上患者的加入维持支气管扩张剂处理，其严重哮喘在前一年中经历了一种或多次严重哮喘发作”，目前用吸入的皮质类固醇治疗谁，至少另一种维护治疗。 [欧盟分散程序]

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《Prescrire international》 |2019年第206期|共1页
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1. tiotropium (Spiriva Respimat0) and severe asthma from six years of age [J] . Prescrire international . 2019,第206期

机译：Tiotropium（Spiriva Respimat0）和六岁的严重哮喘
2. ONCE-DAILY TIOTROPIUM RESPIMAT (R) ADD-ON TO INHALED CORTICOSTEROIDS +/- LONG-ACTING beta(2)-AGONISTS IMPROVES LUNG FUNCTION AND ASTHMA CONTROL AND REDUCES RISK OF ASTHMA WORSENING IN PATIENTS WITH MODERATE OR SEVERE ASTHMA. [J] . Murphy K., Bensch G., Berger W. E., Annals of allergy, asthma, and immunology . 2014,第5Suppla1期

机译：对吸入的皮质类固醇激素+/-长期服用β（2）激动剂的一次补全性噻托溴铵（R）可改善肺功能和哮喘控制，并减轻中度或重度哮喘患者的哮喘恶化风险。
3. Efficacy and safety of tiotropium in school-age children with moderate-to-severe symptomatic asthma: A systematic review [J] . Rodrigo Gustavo J., Neffen Hugo Pediatric allergy and immunology: official publication of the European Society of Pediatric Allergy and Immunology . 2017,第6期

机译：中毒儿中毒儿童中学对症状哮喘的疗效和安全性：系统审查
4. A study of changes in the impressions of yogo teachers about the condition of school children (aged 6 to 15 years) over a three year period in a prefecture severely affected by the tsunami of March 2011 in Japan [C] . Kamiyama M., Nakatani K., Sato M. World Congress on Resilience. . 2014

机译：瑜戈教师对学童状况（6至15岁）在日本海啸严重影响的三年内瑜戈教师展示的研究
5. Prevalence of Asthma among Minority Population Children Aged 0-17 Years in the United States. [D] . AlAlwan, Jalal. 2015

机译：在美国0-17岁的少数族裔儿童中，哮喘的患病率。
6. Frequency of Tiotropium Bromide Use and Clinical Features of Patients with Severe Asthma in a Real-Life Setting: Data from the Severe Asthma Network in Italy (SANI) Registry [O] . Francesca Puggioni, Luisa Brussino, Giorgio Walter Canonica, 2020

机译：真实环境中严重哮喘患者的噻托溴铵使用和临床特征：意大利严重哮喘网络的数据（SANI）注册表
7. >Frequency of Tiotropium Bromide Use and Clinical Features of Patients with Severe Asthma in a Real-Life Setting: Data from the Severe Asthma Network in Italy (SANI) Registry [O] . Francesca Puggioni, Luisa Brussino, Giorgio Walter Canonica, 2020

机译：>真实环境中严重哮喘患者的噻托溴铵使用和临床特征：意大利严重哮喘网络的数据（SANI）注册表

tiotropium (Spiriva Respimat0) and severe asthma from six years of age

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