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Alcohol use and death from respiratory disease in a prospective Chinese elderly cohort study in Hong Kong

机译:香港预期中国老年队列研究中呼吸系统疾病的酒精使用和死亡

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Objective: In Western settings, moderate drinking is negatively associated with respiratory disease. However, moderate drinking is socially patterned, making this association vulnerable to contextual biases. Evidence from other contexts where the typical drinking pattern is different may clarify such observations. Methods: Multivariable Cox regression analysis was used to assess the adjusted associations of alcohol use with death from respiratory disease using a population-based prospective cohort of 66,820 Chinese aged ≥ 65. years enrolled from July 1998 to December 2001 at all the 18 Elderly Health Centers of the Hong Kong Government Department of Health and followed till May 30, 2012. Results: During ten-year follow-up, 4065 deaths from respiratory disease occurred. Most current drinkers were occasional drinkers (< 1. day/week). Both moderate and occasional drinking (< 1. day/week) were associated with a lower risk of death from respiratory disease, but the point estimates and pattern of associations were similar between these two types of drinkers. Conclusion: The typical drinking pattern, i.e. occasional drinking (< 1. day/week), which is unlikely to have any biological effect, was similarly associated with a lower risk of respiratory disease as moderate alcohol use, suggesting the attributes of being a typical drinker may be protective.
机译:目的:在西方环境中,中等饮酒与呼吸系统疾病负相关。然而,适度饮酒是社会模式的,使这个关联使得这种关联容易受到上下文偏见的影响。来自其他语境的证据,其中典型的饮酒模式不同可以阐明这些观察结果。方法:多变量Cox回归分析用于利用66,820名≥65岁≥65岁≥65岁的呼吸道疾病死亡的调整后的醇类使用联想。年龄在1998年7月至2001年12月,在所有18名老年卫生中心入学香港政府卫生署,截至2012年5月30日。结果:在十年后续随访期间,呼吸系统疾病的4065例发生死亡。大多数当前的饮酒者都是偶尔的饮酒者(<1。/星期)。中等和偶尔饮酒(<1。日/周)与呼吸系统疾病的死亡风险较低,但这两种饮酒者之间的观点估计和协会模式相似。结论:典型的饮酒模式,即偶尔饮酒(<1日/周),不太可能具有任何生物效应,与呼吸道疾病的风险较低,呼吸疾病的风险与中等酒精使用相似,表明是典型的属性饮酒者可能是保护的。

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