...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >High-throughput ambulatory assessment of digital reactive hyperemia: concurrent validity with known cardiovascular risk factors and potential confounding.
【24h】

High-throughput ambulatory assessment of digital reactive hyperemia: concurrent validity with known cardiovascular risk factors and potential confounding.

机译：数字反应性高血压的高通量动态评估：具有已知的心血管危险因素和潜在混杂性的并行有效性。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: Reactive hyperemia index (RHI) measurement through digital peripheral arterial tonometry (PAT) is proposed for cardiovascular disease (CVD) risk screening. We evaluated the concurrent validity of RHI, measured in a high-throughput ambulatory setting, with known CVD risk factors and biomarkers. METHODS: PAT was included in the 2007 EADS/Augsburg (Germany) cohort follow-up. CVD risk factors (age, sex, hypertension, hyperlipidemia, diabetes, smoking, physical activity, prevalent coronary heart disease, family history, cholesterol, triglycerides, blood pressure (BP), waist-to-hip ratio (WHR)) and biomarkers (d-dimers, fibrinogen, log(c-reactive protein)) were assessed. The relationship between RHI and CVD risk factors and biomarkers was evaluated using multivariate linear regression, controlling for potential confounders (time of day, time since subject's last meal, baseline heart rate, examiner). RESULTS: Of 926 subjects approached, 710 underwent PAT and 603 (mean age 44.9+/-10 years, 88.7% men) with complete data were included for analysis. RHI was significantly related to being female (beta=0.128, p=0.02), low-density lipoprotein cholesterol (beta=-0.001, p=0.02), systolic BP (beta=0.007, p<0.001), WHR (beta=-1.04, p<0.01), time of day (beta=-0.011, p=0.04) and time since last meal (beta=0.013, p<0.01). CONCLUSIONS: Concurrent validity was partially demonstrated, while the need to control for potential confounding was reinforced. Participation was high and may be higher in less time-constrained settings.
机译：目的：通过数字外周动脉术（PAT）进行反应性高血量指数（RHI）测量（PAT），用于心血管疾病（CVD）风险筛查。我们评估了RHI的并发有效性，在高通量的动态环境中测量，具有已知的CVD危险因素和生物标志物。方法：Pat于2007年EADS / AUGSBURG（德国）队列随访。 CVD危险因素（年龄，性，高血压，高脂血症，糖尿病，吸烟，体育锻炼，普遍冠心病，家族史，胆固醇，甘油三酯，血压（BP），腰背率（WHR））和生物标志物（评估D-二聚体，纤维蛋白原，对数（C反应蛋白））。利用多元线性回归评估了RHI和CVD风险因素和生物标志物之间的关系，控制潜在混淆（日期，自受试者最后一餐，基线心率，审查员）的时间。结果：926个受试者接近，710名PAT和603（平均年龄为44.9 +/- 10岁，88.7％的男子）进行分析。 RHI与雌性显着相关（β= 0.128，p = 0.02），低密度脂蛋白胆固醇（β= -0.001，p = 0.02），收缩性BP（β= 0.007，P <0.001），WHR（β= - 1.04，p <0.01），一天时间（β= -0.011，p = 0.04）和自上一餐以来的时间（β= 0.013，P <0.01）。结论：并发有效性是部分展示的，虽然加强了控制潜在混杂的必要性。参与度高，在更少的时间限制环境中可能更高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号