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Impact of Fat-Free Adipose Tissue on the Prevalence of Low Muscle Mass Estimated Using Calf Circumference in Middle-Aged and Older Adults

机译:无脂肪脂肪组织对中老年人和老年人估计的低肌肉质量普遍存在的影响

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摘要

Previous studies proposed calf circumference cutoff values for predicting dual-energy X-ray absorptiometry (DXA)-derived low muscle mass. However, DXA-derived appendicular lean mass (aLM) includes non-skeletal muscle components such as the appendicular fat-free component of adipose tissue fat cells (aFFAT). The purpose of this study was to compare the calf circumference method of classification before (Model #1) and after (Model #2) eliminating the influence of FFAT in healthy Japanese adults (50 to 79 years; mean age 70 (SD 7) years). Model 1, and Model 2 for classifying low muscle mass had a sensitivity of 78% and 64%, specificity of 76% and 75%, positive predictive value of 31% and 28%, and negative predictive value of 96% and 93%, respectively. Appendicular fat-free component of adipose tissue has the potential to influence the ability of calf circumference to accurately classify individuals with low muscle mass. Consideration should be made when using this as a screening tool for low muscle mass.
机译:以前的研究提出了用于预测双能X射线吸收术(DXA)的低肌肉质量的小腿周长截止值。然而,DXA衍生的附属贫质量(ALM)包括非骨骼肌组分,例如脂肪组织脂肪细胞的附奇无脂肪组分(染色)。本研究的目的是比较之前(型号#1)和(模型#2)之前的分类的小牛周长方法消除了FFAT在健康日本成年人中的影响(50至79岁;意味着70岁(SD 7)年)。第1型和模型2,用于分类低肌肉质量的敏感性为78%和64%,特异性为76%和75%,阳性预测值31%和28%,负预测值为96%和93%,分别。脂肪组织的阑尾无脂肪组分具有影响小腿周长以准确分类具有低肌肉质量的个体的能力。应考虑作为低肌肉质量的筛选工具。

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