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Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development

机译：新型冠状病毒2019-NCOV的出现：需要快速疫苗和生物学发展

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摘要

Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. Due to the increasing number of cases in China and outside China, the WHO declared coronavirus as a global health emergency. Nearly 35,000 cases were reported and at least 24 other countries or territories have reported coronavirus cases as early on as February. Inter-human transmission was reported in a few countries, including the United States. Neither an effective anti-viral nor a vaccine is currently available to treat this infection. As the virus is a newly emerging pathogen, many questions remain unanswered regarding the virus's reservoirs, pathogenesis, transmissibility, and much more is unknown. The collaborative efforts of researchers are needed to fill the knowledge gaps about this new virus, to develop the proper diagnostic tools, and effective treatment to combat this infection. Recent advancements in plant biotechnology proved that plants have the ability to produce vaccines or biopharmaceuticals rapidly in a short time. In this review, the outbreak of 2019-nCoV in China, the need for rapid vaccine development, and the potential of a plant system for biopharmaceutical development are discussed.
机译：新型冠状病毒（2019-NCOV）是2019年12月下旬在中国武汉首次确定的新兴病原体。该病毒负责持续爆发，导致人类中严重的呼吸道疾病和肺炎的感染。由于中国和中国以外的案件越来越多，谁宣布了冠状病毒作为全球健康紧急情况。报告了近35,000例案件，至少24个其他国家或地区已在2月初报告冠状病毒病例。在包括美国在内的几个国家/地区报告了人类的跨境传输。目前没有有效的抗病毒性和疫苗可用于治疗这种感染。随着病毒是一种新出现的病原体，对病毒的储层，发病机制，传播性以及更为未知的许多问题仍未得到答复。研究人员的合作努力需要填补这个新病毒的知识差距，以制定适当的诊断工具，有效治疗这种感染。植物生物技术的最新进展证明，植物能够在短时间内快速生产疫苗或生物制药。在本综述中，讨论了2019年 - NCOV的爆发，需要快速疫苗开发，以及生物制药发展植物系统的潜力。

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