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首页> 外文期刊>Progress in Artificial Intelligence >Reducing Cadmium Accumulation in Plants: Structure-Function Relations and Tissue-Specific Operation of Transporters in the Spotlight
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Reducing Cadmium Accumulation in Plants: Structure-Function Relations and Tissue-Specific Operation of Transporters in the Spotlight

机译：减少植物中的镉积累：在聚光灯下运输器的结构功能关系和组织特异性操作

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摘要

Cadmium (Cd) is present in many soils and, when entering the food chain, represents a major health threat to humans. Reducing Cd accumulation in plants is complicated by the fact that most known Cd transporters also operate in the transport of essential nutrients such as Zn, Fe, Mn, or Cu. This work summarizes the current knowledge of mechanisms mediating Cd uptake, radial transport, and translocation within the plant. It is concluded that real progress in the field may be only achieved if the transport of Cd and the above beneficial micronutrients is uncoupled, and we discuss the possible ways of achieving this goal. Accordingly, we suggest that the major focus of research in the field should be on the structure-function relations of various transporter isoforms and the functional assessment of their tissue-specific operation. Of specific importance are two tissues. The first one is a xylem parenchyma in plant roots; a major "controller" of Cd loading into the xylem and its transport to the shoot. The second one is a phloem tissue that operates in the last step of a metal transport. Another promising and currently underexplored avenue is to understand the role of non-selective cation channels in Cd uptake and reveal mechanisms of their regulation.
机译：镉（CD）存在于许多土壤中，并且在进入食物链时，对人类表示重大健康威胁。降低植物中的CD积累是复杂的，即大多数已知的CD转运蛋白还在Zn，Fe，Mn或Cu等必需营养素的运输中运行。这项工作总结了介于植物内介导CD吸收，径向运输和易位的机制的当前知识。得出结论，如果CD的运输和上述有益的微量营养素未耦合，则可以才能实现该领域的真正进展，并且我们讨论了实现这一目标的可能方法。因此，我们建议，该领域的研究的主要重点应在各种运输同种植体的结构功能关系以及其组织特异性操作的功能评估。特异性重要性是两个组织。第一个是植物根中的木质薄壁症; CD加载到木耳的主要“控制器”及其运输到射击。第二个是在金属运输的最后一步中操作的韧皮型组织。另一个有前途和目前的曝光道的大道是了解非选择性阳离子渠道在CD吸收中的作用，并揭示其监管机制。

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