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首页> 外文期刊>Progress in Artificial Intelligence >Clinicobacteriological evaluation of leprosy patients with 1-5 skin lesions
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Clinicobacteriological evaluation of leprosy patients with 1-5 skin lesions

机译：麻风病患者1-5个皮肤病患者的临床生理学评估

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Background: Mycobacterium leprae is a noncultivable mycobacteria, and diagnosis of the disease is based on its clinical and histopathological characteristics and finding the bacteria in skin scrapings and in biopsies taken from the patients. The aim of this study was to shed light on the clinical classification (based on the number of skin lesions) used extensively in the field where patients classified as paucibacillary (PB) were positive on skin smears and histopathology leading to treatment failure and drug resistance. Methods: In this study, we enrolled untreated 62 leprosy patients with 1-5 skin lesions and did a detailed bacterio-histopathological analysis by slit-skin smears (SSSs) and histopathology. Results: Of 62 patients analyzed, 15 patients came out to be multibacillary (MB) and 47 were PB by SSS and histopathology. Conclusion: The findings of the present study showed that the WHO classification of leprosy based on the number of lesions seems to be inappropriate as it considers a number of MB lesions as PB only, thus misleading the treatment strategies. Hence, it is essential that a comprehensive clinicobacteriological assessment of leprosy cases should be done to ensure the appropriate bacillary status and guiding the appropriate treatment strategy.
机译：背景：菌杆菌是一种不可培养的分枝杆菌，对疾病的诊断基于其临床和组织病理学特征，并在患者中发现皮肤刮痧和活组织检查的细菌。本研究的目的是阐明临床分类（基于皮肤病变的数量）广泛使用的患者在甲状腺炎（PB）的患者上阳性皮肤涂片和组织病理学阳性，导致治疗失败和耐药性。方法：在这项研究中，我们注册了未经处理的62例皮肤病变的62名皮肤病，并通过狭缝皮肤涂片（SSS）和组织病理学进行了详细的细菌组织病理学分析。结果：分析62例患者，15名患者出现多元患者（MB），SSS和组织病理学的47名患者。结论：本研究的结果表明，世卫组织对损伤数量的麻风病分类似乎是不合适的，因为它仅考虑了许多MB病变作为PB，因此误导了治疗策略。因此，必须对麻风病病例进行全面的临床诊断，以确保适当的脑状况，并指导适当的治疗策略。

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