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首页> 外文期刊>U. S. pharmacist >Nifedipine 4 mg/mL in SyrSpend SF PH4 Cherry Flavored Nifedipine is highly sensitive to light, so work efficiently and in subdued lighting.
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Nifedipine 4 mg/mL in SyrSpend SF PH4 Cherry Flavored Nifedipine is highly sensitive to light, so work efficiently and in subdued lighting.

机译：硝苯地平4mg / ml在Syrspend SF pH4樱桃味的硝苯地平对光线高度敏感，因此有效地工作，在柔和的照明中。

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Method of Preparation: Note—Work efficiently and in subdued lighting, as nifedipine is highly sensitive to light. Calculate the required quantity of each ingredient for the total amount to be prepared. Accurately weigh or measure each ingredient. Pulverize the nifedipine to a fine powder. Add a small portion of Syr-Spend SF PH4 Cherry Flavored to the powder and mix well to form a smooth paste. Geometrically, add additional SyrSpend SF PH4 Cherry Flavored to final volume in portions, and mix well after each portion. Package and label. Use: Nifedipine is used in the management of Prinzmetal’s variant angina and chronic stable angina pectoris, hypertension, Raynaud’s phenomenon, preterm labor, and acute myocardial infarction. Packaging: Package in tight, light-resistant containers. Labeling: Keep out of reach of children. Use as directed. Keep at room temperature or refrigerated. Shake well. Discard after [time period]. Stability: A beyond-use date of 92 days may be used for this preparation when it is stored at room temperature or refrigerated temperature and packaged in low-actinic plastic prescription bottles. At the end of a 92-day stability study, 94.03% of the drug remained at room temperature and 90.83% remained at refrigerated temperature. Quality Control: Quality-control assessment can include weight/volume, pH, specific gravity, active drug assay, color, rheologic properties/pourability, physical observation, and physical stability (discoloration, foreign materials, gas formation, mold growth).
机译：准备方法：注释 - 有效和在柔和的照明中，因为NifeDipine对光线高度敏感。计算每种成分的所需量，以便制备总量。准确体重或测量每种成分。将硝苯地平粉碎为细粉末。添加一小部分Syr-Chipt SF pH4樱桃调味于粉末并混合良好以形成光滑的糊状物。几何上，将额外的Syrspend SF PH4樱桃加入到最终体积中，并在每个部分后均匀混合。包和标签。使用：NifeDipine用于Prinzmetal的变异性心绞痛和慢性稳定的心绞痛，高血压，RAYNAUD的现象，早产和急性心肌梗死。包装：封装紧密，耐耐火材料。标签：远离儿童接触。按照指示使用。保持房间温度或冷藏。摇匀。 [时间段]后丢弃。稳定性：当它在室温或冷藏温度储存时，可以使用92天的超越日期，并在低光化塑料处方瓶中包装。在92天的稳定性研究结束时，94.03％的药物仍保持在室温下，90.83％仍保持在冷藏温度下。质量控制：质量控制评估可包括重量/体积，pH，比重，活性药物测定，颜色，流变性能/可再性，物理观察和物理稳定性（变色，异物，气体形成，霉菌生长）。

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  • 来源
    《U. S. pharmacist》 |2020年第2期|共2页
  • 作者

    Loyd V. Allen; Jr.;

  • 作者单位

    College of Pharmacy University of Oklahoma Oklahoma City;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药学;
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