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首页> 外文期刊>Psychiatry Research. Neuroimaging >Morphometric in vivo evidence of thalamic atrophy correlated with cognitive and motor dysfunction in Huntington's disease: The IMAGE-HD study
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Morphometric in vivo evidence of thalamic atrophy correlated with cognitive and motor dysfunction in Huntington's disease: The IMAGE-HD study

机译:亨廷顿疾病认知和运动功能障碍的丘脑萎缩的体内证据(Morpho)相关性:Image-HD研究

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摘要

In Huntington's disease (HD), neurodegeneration causes progressive atrophy to the striatum, cortical areas, and white matter tracts - components of corticostriatal circuitry. Such processes may affect the thalamus, a key circuit node. We investigated whether differences in dorsal thalamic morphology were detectable in HD, and whether thalamic atrophy was associated with neurocognitive, neuropsychiatric and motor dysfunction.
机译:在亨廷顿的疾病(HD)中,神经变性导致纹状体,皮质区域和白质子 - 皮质棘轮电路的成分导致渐进性萎缩。 这些过程可能影响丘脑,键电路节点。 我们研究了HD中是否可检测到背部丘脑形态的差异,以及丘脑萎缩是否与神经认知,神经精神和电动机功能障碍有关。

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