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Longitudinal Associations Between Hearing Loss and General Cognitive Ability: The Lothian Birth Cohort 1936

机译:听力损失与一般认知能力之间的纵向协会:洛锡安出生队队1936年

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Hearing impairment is associated with poorer cognitive function in later life. We tested for the potential contribution of childhood cognitive ability to this relationship. Childhood cognitive ability is strongly related to cognitive function in older age, and may be related to auditory function through its association with hearing impairment risk factors. Using data from the Lothian Birth Cohort. 1936, we tested whether childhood cognitive ability predicted later-life hearing ability then whether this association was mediated by demographic or health differences. We found that childhood cognitive ability was negatively associated with hearing impairment risk at age 76 (odds ratio = .834, p = .042). However, this association was nonsignificant after subsequent adjustment for potentially mediating demographic and health factors. Next, we tested whether associations observed in older age between hearing impairment and general cognitive ability level or change were accounted for by childhood cognitive ability. At age 76. in the minimally adjusted model, hearing impairment was associated with poorer general cognitive ability level (beta = -.119,p = .030) but was not related to decline in general cognitive ability. The former association became nonsignificant after additional adjustment for childhood cognitive ability (beta = -.068, p = .426) suggesting that childhood cognitive ability contributes (potentially via demographic and health differences) to the association between levels of hearing and cognitive function in older age. Further work is needed to test whether early life cognitive ability also contributes to the association (documented in previous studies) between older-age hearing impairment and cognitive decline.
机译:听证障碍与后期生命中的认知功能较差。我们测试了童年认知能力对这种关系的潜在贡献。童年认知能力与年龄较大的认知功能强烈相关,通过与听力损害风险因素的关联可能与听觉功能有关。使用来自洛锡的出生队列的数据。 1936年,我们测试了儿童认知能力是否预测后生命听力能力,那么这种关联是否被人口或健康差异介导。我们发现儿童认知能力与76岁(赔率比率= .834,P = .042)对听力损伤风险负相关。然而,在随后调整后,这种关联因潜在调解人口和健康因素而被显着。接下来,我们测试了在童年认知能力占了在听力损害和一般认知能力水平或变革之间的年龄较老年期间观察到的关联。在76岁。在最微小的模型中,听力障碍与较差的一般认知能力水平有关(Beta = -.119,P = .030),但与一般认知能力的下降无关。在童年认知能力(Beta = -.068,P = .426)的额外调整后,前协会变得不显着,这表明童年认知能力有助于(潜在通过人口统计和健康差异)到老年人的听力和认知功能之间的关联之间的关联年龄。需要进一步的工作来测试早期生命认知能力也有助于旧时代听力障碍和认知衰退之间的协会(以前记载)。

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