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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >The Mediating Effect of Life-style Behaviors on the Association Between Personality Traits and Cardiovascular Disease Mortality Among 29,766 Community-Dwelling Japanese
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The Mediating Effect of Life-style Behaviors on the Association Between Personality Traits and Cardiovascular Disease Mortality Among 29,766 Community-Dwelling Japanese

机译：生命风格行为对29,766社区居民居民性状及心血管疾病死亡与心血管疾病死亡结合的调解效应

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Objective Personality traits have been associated with an increased risk of cardiovascular disease (CVD) mortality as well as life-style-related cardiovascular risk factors. However, the mediating effects of life-style behaviors in the association between personality factors and CVD mortality remain insufficiently understood. The aim of the present study was to examine the mediating effect of life-style behaviors on the association between personality traits and CVD mortality. Methods We conducted a prospective cohort study of 29,766 Japanese adults aged 40 to 64 years at the baseline and followed them up for 20.8 years from 1990 to 2011. Personality was measured using the Japanese version of the Eysenck Personality Questionnaire - Revised Short Form in 1990. We estimated the multivariable hazard ratio and 95% confidence interval for CVD mortality using Cox proportional hazards models, and explored the mediating effects of life-style behaviors (smoking, drinking, body mass index, and time spent walking) on the association between personality traits and CVD mortality. Results We documented 1033 deaths due to CVD during 562,446 person-years of follow-up. Psychoticism represents tough-mindedness, aggressiveness, coldness, a lack of deliberateness, and egocentricity. After adjusting for confounding variables, higher psychoticism was associated with CVD mortality (base model hazard ratio = 1.36, 95% confidence interval = 1.14-1.61, p trend < .001). All the life-style behaviors together mediated this association by 19.2%, with smoking having the greatest effect at 15.7%. For the other personality traits, no significant associations with CVD mortality were found. Conclusion The present study demonstrated that life-style behaviors, especially smoking, partially mediate the association between psychoticism and CVD mortality.
机译：目标人格性状与心血管疾病（CVD）死亡率的风险增加有关，以及生命风格相关的心血管风险因素。然而，生活方式行为在人格因素和CVD死亡率之间的关系中的调解作用仍然不够理解。本研究的目的是检查生活方式行为对人格特质和CVD死亡率结合的调解效果。方法采用40至64岁的预期队列研究，在基线上，从1990年至2011年开始，将其遵循20.8岁。使用日本版的Eysenck人格问卷 - 1990年修订的简短形式来衡量人格。我们估计了使用Cox比例危险模型的CVD死亡率的多变量危险比和95％的置信区间，并探讨了生活方式行为的调解效果（吸烟，饮酒，体重指数和时间花费走路）对人格特质的关联和CVD死亡率。结果我们在562,446人的随访期间记录了1033年死亡人数。精神病主义代表着艰难的心灵，侵略性，寒冷，缺乏冥想和自我心心。调整混淆变量后，更高的精神病症与CVD死亡率有关（基础模型危险比= 1.36,95％置信区间= 1.14-1.61，P趋势<.001）。所有的生活方式行为将此协会介入19.2％，吸烟最大的效果为15.7％。对于其他个性特征，发现没有发现具有CVD死亡率的重要组织。结论本研究表明，生活方式行为，特别是吸烟，部分地调解精神病和CVD死亡率之间的关联。

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