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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >The Relationship of Early-Life Adversity With Adulthood Weight and Cardiometabolic Health Status in the 1946 National Survey of Health and Development
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The Relationship of Early-Life Adversity With Adulthood Weight and Cardiometabolic Health Status in the 1946 National Survey of Health and Development

机译：早期逆境与成年重量和心细差异的关系的关系1946年国家健康与发展调查

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摘要

Objective Evidence linking early-life adversity with an adverse cardiometabolic profile in adulthood is equivocal. This study investigates early-life adversity in relation to weight and cardiometabolic health status at ages 60 to 64 years. Methods We included 1059 individuals from the 1946 National Survey of Health and Development. Data on adversity between ages 0 to 15 years were used to create a cumulative childhood psychosocial adversity score and a socioeconomic adversity score. Cardiometabolic and weight/height data collected at ages 60 to 64 years were used to create four groups: metabolically healthy normal weight, metabolically unhealthy normal weight, metabolically healthy overweight/obese, and metabolically unhealthy overweight/obese. Associations between the two exposure scores and weight/health status were examined using multinomial logistic regression, with adjustment for sex and age at the outcome visit. Results Sixty-two percent of normal-weight individuals were metabolically healthy, whereas only 34% of overweight/obese individuals were metabolically healthy. In a mutually adjusted model including both exposure scores, a psychosocial score of >= 3 (compared with 0) was associated with increased risk of being metabolically unhealthy (compared with healthy) in both normal-weight adults (relative risk = 2.49; 95% confidence interval = 0.87-7.13) and overweight/obese adults (1.87; 0.96-3.61). However, the socioeconomic adversity score was more strongly related to metabolic health status in overweight/obese adults (1.60; 0.98-2.60) than in normal-weight adults (0.95; 0.46-1.96). Conclusions Independently of socioeconomic adversity, psychosocial adversity in childhood may be associated with a poor cardiometabolic health profile, in both normal-weight and overweight/obese adults.
机译：将早年逆境与成年期的不利心脏差异概况联系起来的客观证据是等因素的。本研究调查了60至64岁的重量和心肌素质健康状况的早期逆境。方法我们包括1946年国家健康和发展调查的1059人。在0至15年之间的逆境数据用于创造累计童年的心理社会逆境分数和社会经济逆境得分。在60至64岁处于60至64岁处收集的心脏素和体重/高度数据用于创造四组：代谢健康的正常体重，代谢不健康的正常体重，即代谢性健康超重/肥胖，以及代谢上不健康的超重/肥胖。使用多项逻辑回归检查两种曝光分数和体重/健康状况之间的关联，并在结果访问中调整性和年龄调整。结果，六十二百分之百分之一体的正常个体是代谢健康的，而只有34％的超重/肥胖个体在代谢上健康。在包括曝光得分的相互调整的模型中，心理社会评分> = 3（与0比较）与正常重量成年人（相对风险= 2.49; 95％）的代谢性不健康（与健康相比）的风险增加有关。置信区间= 0.87-7.13）和超重/肥胖成年人（1.87; 0.96-3.61）。然而，社会经济逆境得分与超重/肥胖成年人的代谢健康状况更强烈，而不是正常成人（0.95; 0.46-1.96）。结论独立于社会经济逆境，童年期的心理社会逆境可能与贫困的心脏差异卫生统计概况有关，正常重量和超重/肥胖的成年人。

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