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Relationship Between Different Experimental Measures of Distorted Symptom Perception in Functional Syndrome Patients

机译:功能综合征患者扭曲症状感知的不同实验措施的关系

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Objective Patients with functional somatic syndromes show reduced correspondence between induced physiological changes and self-reported symptoms in a rebreathing paradigm, as well as elevated symptoms unrelated to physiological changes after induction of negative affective states in an affective picture-viewing paradigm. Detailed results of both paradigms separately were published elsewhere. The main goal of the current report is to describe the relationship between the responses to these two paradigms measuring distortions in symptom perception in a well-described sample of patients with fibromyalgia and/or chronic fatigue syndrome. Methods Patients (N = 81) with fibromyalgia and/or chronic fatigue syndrome participated in a test session comprising four well-validated paradigms, including the picture-viewing and rebreathing paradigm. Using mixed model analyses, we tested whether the amount of affective modulation of symptom reporting was related to distorted perception of induced dyspnea. In an exploratory way, we assessed the role of several individual difference variables as moderators. Results There was no relationship between patients' amount of affective modulation of symptom reporting, as assessed with the picture paradigm, and level of distortion in dyspnea perception, as assessed with the rebreathing paradigm (effect of affective modulation in the subjective recovery from induced dyspnea: F-1,F-70 = 0.16, p = .70; time by affective modulation interaction effect: F-4,F-70 = 0.14, p = .97). Conclusions Biased symptom reporting in one paradigm is unrelated to biased symptom reporting in the other paradigm, indicating that distortions in symptom perception in patients with functional somatic syndromes are not a trait-like, cross-situationally stable condition, but a versatile dysfunction that is context dependent.
机译:目的官能体综合征的患者表现出诱导的生理变化和肠道范式中的自我报告症状之间的对应关系,以及在情感图像观察范式中诱导负面情感状态后与生理变化无关的升高症状。分别在其他地方公布了两个范例的详细结果。目前报告的主要目的是描述对这两种范例之间的反应之间的关系,这些两种范例测量症状在纤维肌痛和/或慢性疲劳综合征的患者博语样本中的症状感知中的畸变。方法患者(n = 81)与纤维肌痛和/或慢性疲劳综合征参加了包含四种良好验证的范式的测试会议,包括图片观看和rebbenting范式。使用混合模型分析,我们测试了症状报告的情感调节量是否与诱导呼吸困难的扭曲感知有关。在探索性的方式中,我们评估了几个个体差分变量作为主持人的作用。结果患者对症状报告的情感调节量之间没有关系,与图像范式评估,随着呼吸困难范式的评估(情感调节在诱导呼吸困难中的主观恢复中的影响: F-1,F-70 = 0.16,P = .70;通过情感调制相互作用的时间:F-4,F-70 = 0.14,p = .97)。结论在一个范式中的偏见症状报告与其他范例偏见的症状报告无关,表明患有功能性躯体综合征患者的症状感知的扭曲不是特性,交叉情境稳定的病症,而是一种是上下文的多功能功能障碍依赖。

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