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首页> 外文期刊>Ultrasound in Medicine and Biology >ULTRASENSITIVE ULTRASOUND MICROVESSEL IMAGING FOR CHARACTERIZING BENIGN AND MALIGNANT BREAST TUMORS
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ULTRASENSITIVE ULTRASOUND MICROVESSEL IMAGING FOR CHARACTERIZING BENIGN AND MALIGNANT BREAST TUMORS

机译：用于表征良性和恶性乳腺肿瘤的超声敏感超声微血管成像

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摘要

Tumor angiogenesis plays an important role during breast tumor growth. However, conventional Doppler has limited sensitivity to detect small blood vessels, resulting in a large overlap of Doppler features between benign and malignant tumors. An ultrasensitive ultrasound microvessel imaging (UMI) technique was recently developed. To evaluate the performance of UMI, we studied 44 patients with 51 breast masses. Tumor pathology served as the gold standard: 28 malignancies and 23 benignities. UMI provided a significant improvement in depicting smaller vessels compared with conventional Doppler. The microvessel morphologies observed on UMI were associated with tumor benign/malignant classification. The diagnostic accuracy of correct Breast Imaging Reporting and Data System (BI-RADS) classification rate (BI-RADS >= 4a: test positive; BI-RADS <= 3: test negative) as a fraction of total mass population was improved by 16% after combining conventional ultrasound with UMI compared with using conventional ultrasound alone. This improvement indicates the potential of UMI in reducing unnecessary benign biopsies and avoiding missed malignant biopsies. (C) 2019 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
机译：肿瘤血管生成在乳腺肿瘤生长期间起着重要作用。然而，常规多普勒对检测小血管的敏感性有限，导致良性和恶性肿瘤之间的多普勒特征大幅重叠。最近开发了超声敏感的超声微型微型胶体成像（UMI）技术。为了评估UMI的性能，我们研究了44名患有51例胸部肿块的患者。肿瘤病理为黄金标准：28个恶性肿瘤和23个祝福。 UMI提供了与传统多普勒相比描绘较小血管的显着改进。在UMI上观察到的微血管形态与肿瘤良性/恶性分类有关。正确乳房成像报告和数据系统（BI-RADS）分类率的诊断准确性（Bi-rads> = 4a：测试阳性; Bi-rads <= 3：试验阴性）作为总质量群的一小部分得到16与单独使用常规超声相比，将传统超声与UMI组合后％。这种改进表明UMI在减少不必要的良性活检中并避免错过的恶性生物检查。 （c）2019年中国医学与生物学超声联联合会。版权所有。

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