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首页> 外文期刊>Ultrasound in Medicine and Biology >Contrast-Enhanced Intravascular Ultrasound Pulse Sequences for Bandwidth-Limited Transducers
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Contrast-Enhanced Intravascular Ultrasound Pulse Sequences for Bandwidth-Limited Transducers

机译：带宽有限换能器的对比度增强的血管内超声脉冲序列

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摘要

We demonstrate two methods for vasa vasorum imaging using contrast-enhanced intravascular ultrasound, which can be performed using commercial catheters. Plaque neovascularization was recognized as an independent marker of coronary artery plaque vulnerability. IVUS-based methods to image the microvessels available to date require high bandwidth (-6 dB relative frequency bandwidth >70%), which are not routinely available commercially. We explored the potential of ultraharmonic imaging and chirp reversal imaging for vasa vasorum imaging. In vitro recordings were performed on a tissue-mimicking phantom using a commercial ultrasound contrast agent and a transducer with a center frequency of 34 MHz and a -6 dB relative bandwidth of 56%. Acoustic peak pressures <500 kPa were used. A tissue-mimicking phantom with channels down to 200 μm in diameter was successfully imaged by the two contrast detection sequences while the smallest channel stayed invisible in conventional intravascular ultrasound images. Ultraharmonic imaging provided the best contrast agent detection.
机译：我们用对比增强的血管内超声证明了两种用于VASA血管成像的方法，这可以使用商业导管进行。斑块新生血管化被认为是冠状动脉斑块脆弱性的独立标记。基于IVUS的图像用于图像可用的微型搜索需要高带宽（-6 dB的相对频率带宽> 70％），这不是商业上的。我们探讨了超声成像和啁啾逆转成像对VASA血管成像的潜力。使用商业超声造影剂和中心频率为34MHz的中心频率和换能器进行体外录制，以34MHz的中心频率和-6dB的相对带宽为56％。使用声学峰值压力<500kPa。两种对比度检测序列成功地成功地成功成像了直径下至200μm的组织模拟幻像，而在常规的血管内超声图像中最小的通道保持不可见。超声成像提供了最佳的造影剂检测。

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