...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Ultrasound in Medicine and Biology >DIAGNOSTIC PERFORMANCE OF SHEAR WAVE ELASTOGRAPHY PARAMETERS ALONE AND IN COMBINATION WITH CONVENTIONAL B-MODE ULTRASOUND PARAMETERS FOR THE CHARACTERIZATION OF THYROID NODULES: A PROSPECTIVE, DUAL-CENTER STUDY
【24h】

DIAGNOSTIC PERFORMANCE OF SHEAR WAVE ELASTOGRAPHY PARAMETERS ALONE AND IN COMBINATION WITH CONVENTIONAL B-MODE ULTRASOUND PARAMETERS FOR THE CHARACTERIZATION OF THYROID NODULES: A PROSPECTIVE, DUAL-CENTER STUDY

机译：单独剪切波形弹性摄影参数的诊断性能，以及与常规B模式超声参数的结合甲状腺结节表征：一项前瞻性，双中心研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aims of our study were to determine whether shear wave elastography (SWE) can improve the conventional B-mode differentiation of thyroid lesions, determine the most accurate SWE parameter for differentiation and assess the influence of microcalcifications and chronic autoimmune thyroiditis on SWE values. We examined 119 patients with 169 thyroid nodules who prospectively underwent B-mode ultrasound and SWE using the same ultrasound machine. The parameters assessed using SWE were: mean elasticity within the entire lesion (SWE-whole) and mean (SWE-mean) and maximum (SWE-max) elasticity for a 2-mm-diameter region of interest in the stiffest portion of the lesion, excluding microcalcifications. The discriminant powers of a generalized estimating equation model including B-mode parameters only and a generalized estimation equation model including both B-mode and SWE parameters were assessed and compared using the area under the receiver operating characteristic curve, in association with pathologic verification. In total, 50 and 119 malignant and benign lesions were detected. In generalized estimated equation regression, the B-mode parameters associated with higher odds ratios (ORs) for malignant lesions were microcalcifications (OR = 4.3), hypo-echogenicity (OR = 3.13) and irregular margins (OR = 10.82). SWE-max was the only SWE independent parameter in differentiating between malignant and benign tumors (OR = 2.95). The area under the curve for the B-mode model was 0.85, whereas that for the model combining B-mode and SWE parameters was 0.87. There was no significant difference in mean SWE values between patients with and without chronic autoimmune thyroiditis. The results of the present study suggest that SWE is a valuable tool for the characterization of thyroid nodules, with SWE-max being a significant parameter in differentiating benign and malignant lesions, independent of conventional B-mode parameters. The combination of SWE parameters and conventional B-mode parameters does not significantly improve the diagnosis of malignant thyroid nodules. The presence of microcalcifications can influence the SWE-whole value, whereas the presence of chronic autoimmune thyroiditis may not. (E-mail: kdsobczak@gmail.com) (C) 2016 World Federation for Ultrasound in Medicine & Biology.
机译：我们研究的目的是确定剪力波弹性摄影（SWE）是否可以改善甲状腺病变的常规B模式分化，确定分化的最精确的SWE参数，并评估微钙化和慢性自身免疫甲状腺炎对SWE值的影响。我们检查了119例患者169例甲状腺结节，使用相同的超声波展示了B模式超声波和SWE。使用SWE评估的参数是：在整个病变（SWE-整体）和平均值（SWE-平均值）和最大（SWE-MEAL）和最大（SWE-MAX）弹性内的平均弹性，用于在损伤的最基地，不包括微钙化。仅评估包括B模式参数的广义估计等式模型的判别功率以及包括B模式和SWE参数的广义估计方程模型，并使用接收器操作特性曲线下的区域与病理验证相关联进行比较。总共，检测到50％和119个恶性和良性病变。在广义估计方程回归中，与较高的恶性病变较高的差异比率（或）相关的B模式参数是微钙化（或= 4.3），低回声（或= 3.13）和不规则的边缘（或= 10.82）。 Swe-Max是唯一的SWE独立参数，用于区分恶性和良性肿瘤（或= 2.95）。 B模式模型的曲线下的区域为0.85，而对于组合B模式和SWE参数的模型为0.87。没有慢性自身免疫甲状腺炎的患者之间的平均SWE值没有显着差异。本研究结果表明，SWE是甲状腺结节表征的宝贵工具，SWE-MAX是差异良性和恶性病变的重要参数，与传统的B模式参数无关。 SWE参数和常规B模式参数的组合没有显着改善恶性甲状腺结节的诊断。微钙化的存在可以影响蜂鸣性的价值，而慢性自身免疫甲状腺炎的存在可能不是。 （电子邮件：kdsobczak@gmail.com）（c）2016年度超声波医学与生物学联合会。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号