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首页> 外文期刊>Taiwan Veterinary Journal >CYTOKERATIN PROFILES OF CANINE ANAL SAC AND HEPATOID GLAND NEOPLASMS
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CYTOKERATIN PROFILES OF CANINE ANAL SAC AND HEPATOID GLAND NEOPLASMS

机译：Canine肛门囊和肝腺瘤的细胞角蛋白曲线

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摘要

Ten adenocarcinomas of the apocrine gland of the anal sac and 11 hepatoid gland neoplasms were studied to determine the coordinate expression of cytokeratin 7 (CK7) and cytokeratin 14 (CK14) using commercially available antibodies. Hepatoid gland neoplasms included hepatoid gland adenomas, carcinomas and a single epithelioma. All 10 (100%) adenocarcinomas of the apocrine gland of the anal sac had CK7+/CK14? immunophenotype, whereas all 11 (100%) of hepatoid neoplasms expressed CK7?/CK14+ immunophenotype. Hepatoid gland adenomas, carcinomas, and epithelioma could not be differentiated based on the cytokeratin immunophenotype. Hepatoid gland neoplasms could be differentiated from adenocarcinomas of the apocrine gland of the anal sac by differences in the CK7/CK14 immunophenotypes with a p-value=0.00. The results of this study provide further support for the use of coordinate expression of CK7/CK14 to differentiate apocrine gland adenocarcinomas of the anal sac (CK7+/CK14?) from hepatoid gland neoplasms (CK7?/CK14+).
机译：研究了肛门囊和11个肝腺肿瘤的腺分子腺体的十个腺癌，以确定使用市售抗体的细胞角蛋白7（CK7）和细胞角蛋白14（CK14）的坐标表达。肝脏腺体肿瘤包括肝脏腺瘤，癌症和单一的上皮细胞瘤。 Anal Sac的Anocrine腺体的所有10（100％）腺癌具有CK7 + / CK14？免疫蛋白型，而所有11（100％）的肝肿瘤表达CK7？/ CK14 +免疫蛋白型。肝脏腺瘤，癌和上皮细胞瘤不能根据细胞角蛋白免疫蛋白型不分化。肝脏腺瘤可以通过肛门囊的腺癌腺癌通过CK7 / CK14免疫蛋白酶型具有p值= 0.00的差异来分化。本研究的结果提供了进一步支持使用CK7 / CK14的坐标表达，从肝固体肿瘤（CK7？/ CK14 +）中分化肛门囊（CK7 + / CK14）的肛门囊腺癌（CK7 + / CK14）的组成腺腺癌。

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