Changes in expressions of ADAM9, 10, and 17 as well as alpha-secretase activity in renal cell carcinoma

Erin Nuray; Ipekci Tumay; Akkaya Bahar; Ozbudak Irem Hicran; Baykara Mehmet

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Changes in expressions of ADAM9, 10, and 17 as well as alpha-secretase activity in renal cell carcinoma

机译：ADAM9,10和17表达的变化以及肾细胞癌中的α-分泌酶活性

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Background: ADAM9, 10, and 17 are a class of disintegrins and metallproteinases with oc-secretase activity. There are conflicting results regarding the role(s) of ADAM9, 10, and 17 in carcinogenesis, and only a few studies have examined their levels and cellular localization in renal cell carcinoma (RCC). Studies examining changes in oc-secretase activity in RCC compared to enzymatic activity of the uninvolved kidney are lacking.

机译：背景：ADAM9,10和17是一类脱丁基锡和具有OC分泌酶活性的金属蛋白酶。关于癌症中的Adam9,10和17的作用存在矛盾的结果，并且只有少数研究检测了肾细胞癌（RCC）的水平和细胞定位。缺乏研究RCC中癌症突毒酶活性的变化，而缺乏未植入的肾脏的酶活性。

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来源
《Urologic oncology》 |2017年第1期|共1页
作者
Erin Nuray; Ipekci Tumay; Akkaya Bahar; Ozbudak Irem Hicran; Baykara Mehmet;
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作者单位

Akdeniz Univ Sch Med Dept Med Pharmacol Antalya Turkey;

Baskent Univ Dept Urol Alanya Turkey;

Akdeniz Univ Sch Med Dept Urol Antalya Turkey;

Baskent Univ Dept Urol Alanya Turkey;

Akdeniz Univ Sch Med Dept Pathol Antalya Turkey;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
alpha-Secretase; ADAM10; ADAM9; ADAM17; Renal cell carcinoma; Human;

机译：α-分泌酶;ADAM10;ADAM9;ADAM17;肾细胞癌;人类;

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1. Changes in expressions of ADAM9, 10, and 17 as well as alpha-secretase activity in renal cell carcinoma [J] . Erin Nuray, Ipekci Tumay, Akkaya Bahar, Urologic oncology . 2017,第1期

机译：ADAM9,10和17表达的变化以及肾细胞癌中的α-分泌酶活性
2. 575 Alpha-secretase and neprilysin enzyme activities are decreased in renal cell carcinoma [J] . N.Erin, T.Ipek?i, B.K.Akkaya, European Journal of Cancer Supplements . 2010,第5期

机译：575在肾细胞癌中α-分泌酶和中性溶酶的活性降低
3. 48 POSTER Distinct gene expression profiles and cell death pathways in clear-cell renal cell carcinoma (CCRCC) and colorectal carcinoma (CRC) cells:r elationship to hypoxia, von Hippel Lindau protein (pVHL) expression and anti-tumor activity of sorafenib [J] . R.Ganapathi, A.Al-Hazzouri, S.Vaziri, European Journal of Cancer Supplements . 2006,第12期

机译：48透明细胞肾细胞癌（CCRCC）和结直肠癌（CRC）细胞中POSTER的不同基因表达谱和细胞死亡途径：与缺氧的关系，von Hippel Lindau蛋白（pVHL）的表达和索拉非尼的抗肿瘤活性
4. Application of High-Throughput Sequencing Data Mining in Comparison of Gene Expression Profile in Renal Cell Carcinoma and Normal Renal Cell by RNA-Seq [C] . Yunhai Yu, Hongmei Xu, Shaoning Guo, International Conference on Innovative Computing . 2020

机译：高通量测序数据挖掘在RNA-SEQ肾细胞癌和正常肾细胞中基因表达谱的比较中的应用
5. The regulation of gene expression profiles in clear cell renal cell carcinoma by tumor heterogeneity and environmental exposure. [D] . Brooks, Samira A. 2015

机译：肿瘤异质性和环境暴露对透明细胞肾细胞癌基因表达谱的调节。
6. MicroRNA-30a suppresses the proliferation migration and invasion of human renal cell carcinoma cells by directly targeting ADAM9 [O] . Lining Jiang, Yabin Liu, Can Ma, -1

机译：MicroRNA-30a通过直接靶向ADAM9抑制人肾细胞癌细胞的增殖迁移和侵袭
7. MicroRNA‑30a suppresses the proliferation, migration and invasion of human renal cell carcinoma cells by directly targeting ADAM9 [O] . Lining Jiang, Yabin Liu, Can Ma, 2018

机译：MicroRNA-30A通过直接瞄准ADAM9抑制人肾细胞癌细胞的增殖，迁移和侵袭

Changes in expressions of ADAM9, 10, and 17 as well as alpha-secretase activity in renal cell carcinoma

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