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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Clinical Features, Diagnosis, and Outcome of Encephalitis in French Guiana
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Clinical Features, Diagnosis, and Outcome of Encephalitis in French Guiana

机译：法国圭亚那脑炎的临床特征，诊断和结果

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The aim of our study was to describe the clinical features, the etiologies, and the factors associated with poor outcome of encephalitis in French Guiana. Our study was retrospective, including all cases of encephalitis hospitalized in the Cayenne General Hospital, from January 2007 to July 2017. Patients were included through the 2013 encephalitis consortium criteria and the outcome was evaluated using the Glasgow outcome scale at 3 months from the diagnosis of encephalitis. We included 108 patients, giving an approximate incidence rate of four cases/ 100,000 inhabitants/year. The origin of the encephalitis was diagnosed in 81 cases (75%), and 72 of them (66.7%) were from an infectious origin. The most common infectious causes were Cryptococcus sp. (18.5%) independently of the immune status, Toxoplasma gondii (13.9%), and Streptococcus pneumoniae (5.5%). In the follow-up, 48 patients (46.6%) had poor outcome. Independent risk factors associated with poor outcome at 3 months were "coming from inside area of the region" (P = 0.036, odds ratio [OR] = 4.19; CI 95% = 1.09-16.06), need for mechanical ventilation (P = 0.002, OR = 5.92; CI 95% = 1.95-17.95), and age (3) 65 years (P = 0.049, OR = 3.99; CI 95% = 1.01-15.89). The most identified cause of encephalitis in French Guiana was Cryptococcus. The shape of the local epidemiology highlights the original infectious situation with some local specific pathogens.
机译：我们的研究目的是描述法国圭亚那脑炎患者疾病差异的临床特征，病因和因素。我们的研究是回顾性的，包括从2007年1月到2017年1月到2017年7月住院的所有脑炎病例。患者通过2013年脑炎联盟标准，并在诊断中使用Glasgow结果评估了结果。脑炎。我们包括108名患者，给出四种案例/ 100,000名居民/年的近似发生率。脑炎的起源被诊断为81例（75％），其中72例（66.7％）来自传染性起源。最常见的传染病是Cryptococcus sp。 （18.5％）独立于免疫状态，弓形虫（13.9％）和链球菌肺炎（5.5％）。在随访中，48名患者（46.6％）的结果差。与3个月的差的差异有关的独立风险因素是“来自区域内部区域”（P = 0.036，差距[或] = 4.19; CI 95％= 1.09-16.06），需要机械通气（P = 0.002 ，或= 5.92; CI 95％= 1.95-17.95），年龄（3）65岁（P = 0.049，或= 3.99; CI 95％= 1.01-15.89）。法国圭亚那中脑炎最识别的原因是隐睾。当地流行病学的形状突出了一些局部特定病原体的原始传染性局面。

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