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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >The Unmet Need: Low Performance of Laboratory Professionals in Malaria Microscopy, Oromia Regional State, Ethiopia
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The Unmet Need: Low Performance of Laboratory Professionals in Malaria Microscopy, Oromia Regional State, Ethiopia

机译:未满足的需求:疟疾中的实验室专业人士的低性能,奥罗米亚地区国家,埃塞俄比亚

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摘要

Ethiopia aims to diagnose and treat all clinical malaria within 24 hours of fever onset in its stride to eliminate the disease by 2030. Microscopy remains to be the mainstay for diagnosis at the health center and hospital level. Continuous evaluation and performance upgrading of malaria microscopists is one of the cornerstones in this effort. We assessed the performance of malaria microscopists compared with reference readers in diagnosing, identifying the species, and quantifying parasitemia. A total of 174 microscopists were enrolled from health facilities located in 86 districts in Oromia region (Ethiopia) from January 2017 to June 2018. Panel slides with known Plasmodium species, diagnostic blood stage, and parasite density were prepared by the reference readers. Sociodennographics, education, inservice training, and routine practice of participants were captured. Sensitivity, specificity, percent agreement, and kappa score were calculated. An overall low performance was observed that could threaten the malaria diagnostic service. Of all the slides distributed (1,218), only 17.0% of the positive and 30.0% of the negative slides were correctly identified and 22.4% were correctly quantified. Compared with the reference readers, participants had lower competence in diagnosing (74.3% agreement and kappa 0.45) and identifying the species (71.2% agreement and kappa 0.40). Two-fifths of the participants were graded as "in training" with respect to identifying the species (41.0%) and the diagnostic stages (40.0%). An in-service training/retraining and supportive supervision are needed to raise and maintain the competence of microscopists in settings with a recent decline in malaria transmission and aiming for ultimate elimination of the disease.
机译:埃塞俄比亚旨在诊断和治疗所有临床疟疾,在其上升的前进后24小时内诊断,以便在2030年之前消除疾病。显微镜仍然是医疗中心和医院水平诊断的主干。疟疾显微镜的持续评估和性能升级是这项工作中的基石之一。我们评估了疟疾显微镜的性能与参考读者诊断,鉴定物种和量化寄生虫血症相比。从2017年1月至2018年6月,共有174名显微镜参加了位于Oromia地区(Etomia)(埃塞俄比亚)的86个地区的卫生设施。用参考读者制备具有已知疟原虫物种,诊断血液阶段和寄生虫密度的面板。捕获了社会生活,教育,Inservice培训和参与者的常规实践。计算敏感性,特异性,百分比和κ评分进行了计算。观察到整体低性能,可能会威胁疟疾诊断服务。在分布的所有载玻片(1,218)中,正确鉴定了17.0%的阳性和30.0%的阴性载玻片,正确量化了22.4%。与参考读者相比,参与者在诊断(74.3%协议和Kappa 0.45)中的竞争力较低,并确定物种(71.2%协议和Kappa 0.40)。参与者的二分之二是关于鉴定物种(41.0%)和诊断阶段(40.0%)的“培训”。需要在疟疾传播最近下降和旨在实现疾病的最终消除疾病的情况下,在环境中培养和维持显微镜师的能力,以便培养和维持显微镜手的能力。

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  • 作者单位

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Oromia Reg Hlth Bur Addis Ababa Ethiopia;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

    Armauer Hansen Res Inst Malaria &

    Neglected Trop Dis Res Directorate Jimma Rd POB 1005 Addis;

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  • 正文语种 eng
  • 中图分类 地方病学;
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