...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Risk Factors for Nontyphi Salmonella Bacteremia Over 10 Years in Fort-de-France, Martinique, West Indies
【24h】

Risk Factors for Nontyphi Salmonella Bacteremia Over 10 Years in Fort-de-France, Martinique, West Indies

机译：在法国堡垒德国，马提尼克岛，西印度群岛的危险因素超过10年。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nontyphoidal Salmonella infections can result in bacteremia. This study was undertaken to determine the predictive factors for bacteremia in children aged less than 16 years. Medical data were collected for every child with positive nontyphoidal Salmonella cultures in blood or stools at the University hospital of Martinique, French West Indies, between January 2005 and December 2015. Among 454 patients, 333 were included; 156 cases had confirmed bacteremia, and 177 were included as control group with nontyphoidal Salmonella only isolated in stools. Age at diagnosis, delay before consulting, prematurity, immunosuppression, or hyperthermic seizures were not significantly associated with bacteremia. C-reactive protein was higher in cases of bacteremia (P = 0.01); however, after adjusting to the threshold of 30 mg/L, there was no longer any difference. There were also significant relations for electrolytes such as hyponatremia (odds ratio (OR) = 2.08 [95% CI = 1.31-3.95]; P < 0.01), high urea level (OR = 0.53 [95% CI = 0.32-0.88], P < 0.01). The infecting serotype was the most discriminant risk factor (P < 10-4). Among 28 serotypes isolated between 2005 and 2015, Salmonella panama was the most common serotype: 122 strains (78.2%) were isolated from bacteremic patients versus 60 (33.9%) from nonbacteremic patients (P < 10(-4)). Salmonella panama was the most important risk factor for bacteremia (OR = 7.37 [95% CI = 3.18-17.1], P < 10(-4)) even after multivariate analysis (OR = 13.09 [95% CI = 5.42-31.59], P < 10-4). After adjusting for bacteremia, S. panama was associated with a significantly higher body temperature than other Salmonella: 39 degrees C (standard deviation [SD] = 0.92) versus 38.2 degrees C [SD = 1.1], linear regression P < 10(-3). Children with Salmonella serotype panama infection were at higher risk of bacteremia than children infected with other Salmonella serotypes.
机译：无型沙门氏菌感染可能导致菌血症。本研究旨在确定少于16岁儿童的菌血症预测因素。在2005年1月至2015年1月至2015年12月，为法国西印度群大学医院血液或粪便中的每个孩子收集了医疗数据。在2015年至12月，454名患者中，包括333名患者; 156例确诊菌血症，177例被包含作为对照组，其中含有无型沙门氏菌粪便。诊断年龄，咨询前延迟，早熟，免疫抑制或高温癫痫发作与菌血症没有显着相关。菌血症病例中的C-反应蛋白较高（P = 0.01）;但是，在调整到30mg / L的阈值后，不再有任何差异。对低钠血症等电解质（OTS比率（或）= 2.08 [95％CI = 1.31-3.95]; P <0.01），高尿素水平（或= 0.53 [95％CI = 0.32-0.88]， P <0.01）。感染血清型是最判别的危险因素（P <10-4）。在2005年至2015年间分离的28个血清型中，沙门氏巴拿马是最常见的血清型：122株（78.2％）与来自非杀菌患者的菌血患者（33.9％）分离出（P <10（4））。 Salmonella panama是菌血症最重要的危险因素（或= 7.37 [95％ci = 3.18-17.1]，p <10（-4）），即使在多变量分析后（或= 13.09 [95％ci = 5.42-31.59]， p <10-4）。在调整菌血症后，S.Panama与其他沙门氏菌的体温显着更高：39摄氏度（标准偏差[SD] = 0.92）与38.2摄氏度，线性回归P <10（-3 ）。沙门氏菌血清型巴拿马感染的儿童比感染其他沙门氏菌血清型感染的儿童更高的菌血症风险。

著录项

  • 来源
  • 作者

    Buteux Arnaud; Nacher Mathieu; Merat Celia; Duc Nguyen; Roze Benoit; Cabie Andre; Olive Claude;

  • 作者单位

    Ctr Hosp Univ Martinique Lab Bacteriol Fort De France Martinique France;

    Univ Guyane EA 3593 Ecosyst Amazoniens &

    Pathol Trop Cayenne France;

    CHU Nantes Serv Parasitol &

    Mycol Nantes France;

    Univ Guyane EA 3593 Ecosyst Amazoniens &

    Pathol Trop Cayenne France;

    Ctr Hosp Univ Martinique Serv Malad Infect &

    Trop Fort De France Martinique France;

    Ctr Hosp Univ Martinique Serv Malad Infect &

    Trop Fort De France Martinique France;

    Ctr Hosp Univ Martinique Lab Bacteriol Fort De France Martinique France;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 地方病学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号