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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Feasibility, Acceptability, and Accuracy of Vaginal Self-Sampling for Screening Human Papillomavirus Types in Women from Rural Areas in Senegal
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Feasibility, Acceptability, and Accuracy of Vaginal Self-Sampling for Screening Human Papillomavirus Types in Women from Rural Areas in Senegal

机译：阴道自我抽样的可行性，可接受性和准确性，用于筛选塞内加尔农村妇女妇女的人乳头瘤病毒

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摘要

Vaginal self-sampling and human papillomavirus (HPV) DNA testing can be useful tools for women with limited access to health care living in sub-Saharan Africa. To assess the feasibility and acceptability of vaginal self-sampling and high-risk HPV prevalence in two villages of central Senegal, women were asked to self-sample vaginal swabs for HPV detection in May, 2016. Vaginal swabs were collected from 133 women and were tested for HPV genotyping. The acceptability rate of vaginal self-sampling was 98.5%, and 99.2% of the women (133/134) used the device correctly. The quality of self-sampling was satisfactory in 100% of the samples; 10.5% of the samples were positive for HPV, including 6% with high-risk HPV types and 4% with low-risk HPV types. This preliminary study indicates that vaginal self-sampling is a valuable strategy for high-risk HPV detection and cervical cancer screening in a population of women not attending gynecologic screening in rural areas of Senegal.
机译：阴道自抽样和人乳头瘤病毒（HPV）DNA检测可以是用于撒哈拉以南非洲撒哈拉以南非洲的医疗保健有限的妇女是有用的工具。 评估阴道自我采样的可行性和可接受性和在塞内加尔中部两个村庄中的阴道自我抽样和高风险HPV患病率，2016年5月妇女对HPV检测进行了自我样本的阴道拭子。阴道拭子从133名女性中收集了阴道拭子 测试HPV基因分型。 阴道自抽样的可接受性率为98.5％，99.2％的女性（133/134）正确使用该装置。 自抽样的质量在100％的样品中令人满意; 10.5％的样品对于HPV为阳性，其中6％具有高风险的HPV类型和4％，具有低风险的HPV类型。 这项初步研究表明，阴道自抽样是一种有价值的高风险HPV检测和宫颈癌筛查，在塞内加尔农村未参加妇科筛查的妇女患者中的患者。

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