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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case Report: Progressive Perforation of the Nasal Septum due to Leishmania major. A Case of Mucosal Leishmaniasis in a Traveler
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Case Report: Progressive Perforation of the Nasal Septum due to Leishmania major. A Case of Mucosal Leishmaniasis in a Traveler

机译：案例报告：鼻内隔的逐步穿孔由于利什曼省主要。 旅行者中的粘液利什曼病

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摘要

This report describes a case of mucosal leishmaniasis caused by Leishmania major with destructive perforation of the nasal septum illustrating the diagnostic challenges of a rare clinical presentation of L. major infection in a traveler. The atypical presentation may have been associated with the use of cortisone as a potential trigger for the progressive destruction of the nasal septum. Leishmaniasis typically manifests itself as one of three classical disease entities—visceral, cutaneous, and mucocu-taneous leishmaniasis. So far about 20 different Leishmania species have been identified as human pathogens and are commonly divided into New World and Old World Leishmania spp. Mucocutaneous leishmaniasis is usually caused by Leishmania spp. of the New World, mainly by representatives of the Leishmania braziliensis complex, and less often by representatives of the Leishmania guyanensis complex, which are only endemic in South and Central America. However, new terms are used to describe the different manifestations of leishmaniasis more accurately—mucosal leishmaniasis (ML) refers to an involvement of mucous membranes in the oral cavity or the upper respiratory tract. Several case studies have shown that species of Old World leishmaniasis may also involve mucosal membranes. There are reports about ML caused by Leishmania donovani, Leishmania infantum, Leishmania tropica, or Leishmania major.
机译：本报告描述了由Leishmania主要引起的粘膜Leishmaniaisis，鼻中隔的破坏性穿孔，说明了旅行者中L.主要感染的罕见临床展示的诊断挑战。非典型呈现可能已经与使用可可子作为鼻中渐进式破坏的潜在触发相关联。 Leishmaniaisis通常表现为三种古典疾病实体 - 内脏，皮肤和粘膜病的嗜利亚症性之一。到目前为止，大约20种不同的莱山西亚物种已被鉴定为人类病原体，通常分为新世界和老世界利什曼斯SPP。削弱的利什曼病通常是由Leishmania SPP引起的。在新世界，主要由莱山西亚巴西的代表，而少数往往由莱山诺曼斯综合体的代表，这只是南部和中美洲的地方。然而，新的术语用于描述Leishmaniaisis更准确的粘膜LeishManiaisis（ML）的不同表现，是指在口腔或上呼吸道中的粘膜累及。几个案例研究表明，旧世界利什曼病的种类也可能涉及粘膜。有关于Leishmania Donovani，Leishmania Infantum，Leishmania Tropica或Leishmania Major造成的ml有关ML。

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