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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case Report: Recrudescence of Plasmodium falciparum in a Primigravida after Nearly 3 Years of Latency
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Case Report: Recrudescence of Plasmodium falciparum in a Primigravida after Nearly 3 Years of Latency

机译：案例报告：在近3年的延迟后泻药中的疟原虫在疟原虫中的复发

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摘要

We present a case of a primigravid woman who presented with Plasmodium falciparum nearly 3 years after she last visited a malaria-endemic region. We review the literature to identify case reports of recrudescent P. falciparum malaria during pregnancy, including those with prolonged latency. Reports of recrudescence of P. falciparum during pregnancy are limited. Plasmodium falciparum infection can persist for years. Recrudescence can occur with waning of immunity following departure from endemic areas. Pregnancy, particularly the primigravid state, is a risk factor for severe infection. A 29-year-old primigravid woman presented with fever and thrombocytopenia during her third trimester of pregnancy. Originally from Ghana, she permanently relocated to the United States 5 years ago. She visited Ghana 2% years ago for 1 month, but otherwise denies travel outside the United States. She says that she previously had malaria more than 10 times, including during her most recent trip to Ghana for which she did not take chemoprophylaxis and recalls being treated with a several-day course of chloroquine. At 29 weeks into an otherwise uncomplicated pregnancy, she developed headache, back pain, dark urine, and fever and was admitted to Saint Vincent Hospital in Worcester, MA, for further evaluation. Physical examination revealed a temperature of 101.4°F, blood pressure of 97/57 mmHg, and heart rate of 114 per minute. She was awake, alert, and oriented and her sclerae were anicteric. Heart examination showed tachycardia with no murmurs. Her respiratory examination was normal and her abdomen was soft and protuberant, corresponding with her gestational age, with no tenderness or splenomegaly noted. Results of the back examination and neurological examination were unremarkable.
机译：我们提出了一种初步女性的案例，该妇女患有疟原虫疟原虫近3年，近3年来参观了疟疾地方区域。我们审查了在怀孕期间识别核心蛋白疟疾疟疾患者报告的文献，包括延迟延迟的人。怀孕期间p. falciparum的复发报告有限。疟原虫感染可能持续多年。在脱离流行区域后，随着免疫力的衰退，可能会发生复发。妊娠，特别是血脂生命状态，是严重感染的危险因素。一名29岁的血脂女性在她怀孕三个月的三个三个月期间发烧和血小板减少症。原本来自加纳，她5年前永久重新安置到美国。她在2％前访问了加纳1个月，但否则否认在美国以外的旅行。她说，她以前有超过10次的疟疾，包括在她最近的加纳旅行期间，她没有服用化学内容，并召回用几天的氯化疗程治疗。在29周内进入另一种不复杂的怀孕，她开发了头痛，背部疼痛，暗尿液和发烧，并被覆盖伍斯特的圣文森特医院，以进一步评估。体格检查显示101.4°F的温度，血压为97/57 mmHg，每分钟114的心率为114。她醒了，警惕，以巩膜为导向，她的巩膜是狂欢的。心脏检查显示心动过速没有杂音。她的呼吸检查正常，她的腹部柔软且突出，与她的孕龄相对应，没有柔软或脾肿大。后检查和神经检查的结果是不起眼的。

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