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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District
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Case Report: Highlighting Male Genital Schistosomiasis (MGS) in Fishermen from the Southwestern Shoreline of Lake Malawi, Mangochi District

机译：案例报告：突出来自Mangochi区马拉维西南海岸线的渔民的男性生殖器血吸虫病（MGS）

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摘要

Urogenital schistosomiasis causes morbidity within the genitalia but is underreported and infrequently examined in men. To draw attention to male genital schistosomiasis (MGS), a longitudinal cohort study was conducted among fishermen along the southwestern shoreline of Lake Malawi. A case series of five participants is presented inclusive of questionnaire interviews, parasitological examinations, ultrasonography, and provision of a standard dose (40 mg/kg) of praziquantel (PZQ) treatment at baseline, 1-, 3-, 6-, and 12-month follow-up time points. Eggs of Schistosoma haematobium were observed in urine or semen across all time points; parasitological diagnostics were bolstered by real-time PCR for Schistosoma DNA in semen and by portable ultrasonography to document putative MGS-associated morbidity. We highlight the importance of developing standard diagnostic tests for MGS and increasing the accessibility of PZQ treatment to men, especially those in at-risk endemic areas.
机译：泌尿生殖器血吸虫病导致生殖器内的发病率，但在男性中被宣布和常常检查。 为了提请注意雄性生殖器血吸虫病（MGS），沿着马拉维湖海岸线的渔民进行纵向队列研究。 提供了五个参与者的案例系列，包括问卷面试，寄生虫检查，超声检查，并在基线，1-，3-，6-和12的吡喹酮（PZQ）治疗的标准剂量（40mg / kg）。 -Month跟进时间点。 在所有时间点的尿液或精液中观察到血吸虫血症的鸡蛋; 通过用于精液的血吸虫DNA的实时PCR促使寄生诊诊断，并通过便携式超声检查给推定的MGS相关的发病率进行记录。 我们强调了为MGS开发标准诊断测试的重要性，并使PZQ治疗的可达性增加对男性，特别是风险流行区域。

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