Severe cutaneous eruptions following the topical use of preparations containing bufexamac: Is it time to reconsider its registration in Australia?

Harris Adam G.; Saikal Samra L.; Scurry Jim; Relic John; Nixon Rosemary L.; Chee Paul

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Severe cutaneous eruptions following the topical use of preparations containing bufexamac: Is it time to reconsider its registration in Australia?

机译：局部使用含Bufexamac的局部使用后的严重皮肤爆发：是时候重新考虑其在澳大利亚的注册时间？

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Despite being a well-recognised cause of allergic contact dermatitis with an embargo in many countries around the world, bufexamac is available over the counter in topical preparations in Australia. We present a series of patients who developed severe cutaneous eruptions after the topical application of bufexamac containing preparations to highlight the potential risks of this medication, as well as advocate for the reconsideration of its registration by the Therapeutic Goods Administration in Australia.

机译：尽管是全世界许多国家的禁运性过敏接触皮炎的经过公认的过敏性接触性，但Bufexamac可在澳大利亚的局部筹备工作中获得。我们展示了一系列患者在Bufexamac含有制剂的局部应用后显影了严重的皮肤喷发，以突出这种药物的潜在风险，以及通过澳大利亚的治疗货物管理局进行重新考虑其注册。

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来源
《The Australasian journal of dermatology》 |2019年第1期|共4页
作者
Harris Adam G.; Saikal Samra L.; Scurry Jim; Relic John; Nixon Rosemary L.; Chee Paul;
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作者单位

John Hunter Hosp Dept Dermatol Newcastle NSW Australia;

John Hunter Hosp Dept Dermatol Newcastle NSW Australia;

John Hunter Hosp Dept Anat Pathol Newcastle NSW Australia;

John Hunter Hosp Dept Dermatol Newcastle NSW Australia;

Skin &

Canc Fdn Inc Occupat Dermatol Res &

Educ Ctr Melbourne Vic Australia;

John Hunter Hosp Dept Dermatol Newcastle NSW Australia;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
关键词
bufexamac; contact dermatitis; drug reaction; non-steroidal anti-inflammatory agents; patch tests;

机译：Bufexamac;接触皮炎;药物反应;非甾体类抗炎剂;贴剂测试;

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专利

1. Severe cutaneous eruptions following the topical use of preparations containing bufexamac: Is it time to reconsider its registration in Australia? [J] . Harris Adam G., Saikal Samra L., Scurry Jim, The Australasian journal of dermatology . 2019,第1期

机译：局部使用含Bufexamac的局部使用后的严重皮肤爆发：是时候重新考虑其在澳大利亚的注册时间？
2. Allergic contact dermatitis to topical preparations of bufexamac [J] . PanY., NixonR. The Australasian journal of dermatology . 2012,第3期

机译：对布非昔马局部制剂的过敏性接触性皮炎
3. Topical Application of 5-Fluorouracil Associated with Distant Seborrheic Dermatitis-like Eruption: Case Report and Review of Seborrheic Dermatitis Cutaneous Reactions after Systemic or Topical Treatment with 5-Fluorouracil [J] . Tyler Werbel, Philip R. Cohen Dermatology and Therapy . 2018,第3期

机译：5-氟尿嘧啶与远距离脂溢性皮炎样爆发相关的局部应用：5-氟尿嘧啶全身或局部治疗后的脂溢性皮炎皮肤反应的病例报告和回顾
4. Role of collagen, complement C3, and C5 on cutaneous wound healing: Topical formulation, preparation, and in-vivo evaluation in experimental rats [D] . Sinno, Hani. 2009

机译：胶原蛋白，补体C3和C5在皮肤伤口愈合中的作用：在实验大鼠中的局部制剂，制备和体内评估
5. Topical Application of 5-Fluorouracil Associated with Distant Seborrheic Dermatitis-like Eruption: Case Report and Review of Seborrheic Dermatitis Cutaneous Reactions after Systemic or Topical Treatment with 5-Fluorouracil [O] . Tyler Werbel, Philip R. Cohen 2018

机译：5-氟尿嘧啶与远距离脂溢性皮炎样爆发相关的局部应用：5-氟尿嘧啶全身或局部治疗后的脂溢性皮炎皮肤反应的病例报告和回顾
6. Oil of Cade — A Topical Application in Eczematous, Impetiginous and Some Other Cutaneous Eruptions [O] . A. CHAPIN 1859

机译：CADE的油 - 湿透，苍蝇和一些其他皮肤爆发的局部应用

Severe cutaneous eruptions following the topical use of preparations containing bufexamac: Is it time to reconsider its registration in Australia?

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