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首页> 外文期刊>The Australasian journal of dermatology >Dermoscopy improves diagnostic accuracy for clinically amelanotic nodules
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Dermoscopy improves diagnostic accuracy for clinically amelanotic nodules

机译：Dermoscopy提高了临床上的诊断准确性，适用于临床疗法结节

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Background/Objectives Amelanotic nodular melanomas are notoriously difficult to diagnose and are responsible for a disproportionate burden of melanoma mortality. It is important to distinguish them from other amelanotic nodules. This study aimed to describe the dermoscopic features of a series of nodular melanomas and other amelanotic nodules and to determine whether dermoscopy improves diagnostic accuracy. Method Retrospective analysis of 150 clinically amelanotic nodules with macroscopic and dermoscopic images. Results In terms of classifying the nodules as malignant, dermoscopy was superior to unaided eye (specificity 89%; 95% CI 71-98% vs 67%; 95% CI 46-83%, P = 0.03). Dermoscopy enhanced sensitivity for the diagnosis of both amelanotic melanoma and SCC. In 19% of cases, using dermoscopy, the most likely diagnosis was changed from incorrect to correct. This included 26% of amelanotic melanomas which had a macroscopic misdiagnosis overturned to the correct diagnosis. Polymorphous vascular structures were more common in malignant nodules. 76% of amelanotic melanomas/Merkel cell carcinomas had polymorphous vessels compared with 38% of SCCs/KAs/BCCs and 22% of benign nodules (P 0.001). Conclusion Dermoscopy improves diagnostic accuracy for amelanotic melanomas and other amelanotic nodules. Although dermoscopy improves diagnostic accuracy for amelanotic melanomas, these aggressive melanomas remain diagnostically difficult.
机译：背景/目标Amelanotic Nodular Melanomas难以诊断，并负责对黑色素瘤死亡率的不成比例的负担。将它们与其他疗法结节区分开来。本研究旨在描述一系列结节黑色素和其他疗法结节的皮肤特征，并确定Dermoscopy是否提高了诊断准确性。方法回顾性分析150例临床和皮肤镜像的临床疗法结节。结果在将结节分类为恶性的情况下，Dermoscopy优于无型眼睛（特异性89％; 95％CI 71-98％Vs 67％; 95％CI 46-83％，P = 0.03）。 Dermoscopy改善了诊断Amelanotic Melanoma和SCC的敏感性。在19％的病例中，使用Dermoscopy，最可能的诊断从不正确改变到纠正。这包括26％的疗法细菌瘤，其具有宏观误诊直移到正确的诊断。多晶血管结构在恶性结节中更常见。 76％的Amelanotic Melanomas / Merkel细胞癌具有多晶型血管，而38％的SCCS / KAS / BCC和22％的良性结节（P <0.001）。结论Dermoscopy提高了疗法型黑素瘤和其他疗法结节的诊断准确性。虽然Dermoscopy提高了Amelanotic Melanomas的诊断准确性，但这些侵略性黑色素瘤仍然难以诊断。

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