Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

Oo Khine Zin; Aung Ye Kyaw; Jenkins Mark A.; Win Aung Ko

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Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

机译：5HTTPR多态性与主要抑郁症和酒精依赖的关联：系统评价和荟萃分析

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Objective: The neurotransmitter serotonin is understood to control mood and drug response. Carrying a genetic variant in the serotonin transporter gene (5HTT) may increase the risk of major depressive disorder and alcohol dependence. Previous estimates of the association of the S allele of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence have been inconsistent.

机译：目的：神经递质血清素应理解为控制情绪和药物反应。在血清素转运蛋白基因（5HTT）中携带遗传变异可能会增加重大抑郁症和酒精依赖性的风险。以前的5httlpr多态性与主要抑郁症和酒精依赖性的等位基因协会的估计存在不一致。

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来源
《The Australian and New Zealand journal of psychiatry》 |2016年第9期|共16页
作者
Oo Khine Zin; Aung Ye Kyaw; Jenkins Mark A.; Win Aung Ko;
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作者单位

Univ Melbourne Melbourne Sch Populat &

Global Hlth Ctr Epidemiol &

Biostat Level 3 207 Bouverie;

Univ Melbourne Melbourne Sch Populat &

Global Hlth Ctr Epidemiol &

Biostat Level 3 207 Bouverie;

Univ Melbourne Melbourne Sch Populat &

Global Hlth Ctr Epidemiol &

Biostat Level 3 207 Bouverie;

Univ Melbourne Melbourne Sch Populat &

Global Hlth Ctr Epidemiol &

Biostat Level 3 207 Bouverie;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Serotonin transporter; 5HTTLPR polymorphism; depression; alcohol dependence; meta-analysis;

机译：血清素转运蛋白;5httlpr多态性;抑郁症;酒精依赖;Meta分析;

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1. Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis [J] . Oo Khine Zin, Aung Ye Kyaw, Jenkins Mark A., The Australian and New Zealand journal of psychiatry . 2016,第9期

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Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

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