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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Co-ingested alcohol and the timing of deliberate self-poisonings
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Co-ingested alcohol and the timing of deliberate self-poisonings

机译：共同摄取酒精和故意自我中毒的时间

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Objective: Investigating diurnal variation in the timing of suicidal behaviours offers opportunity to better understand its various proximal risk factors. Acute use of alcohol is a potent proximal risk factor for suicidal behaviour, though the nature of this risk is poorly understood. The aim of this study was to compare the diurnal variation in time of poison ingestion between deliberate self-poisonings that involve alcohol versus those that do not. Methods: A retrospective analysis of consecutive presentations to a toxicology service following deliberate self-poisoning, 1996–2016. An independent samples Kolmogorov–Smirnov test was performed to test the null hypothesis that the diurnal distribution of poison ingestion time was equal across self-poisonings that did and did not involve alcohol co-ingestion. Presence of circadian rhythmicity was established using cosinor analysis. Results: A total of 11,088 deliberate self-poisoning records, for 7467 patients (60.8% females), were included in the analysis. In all, 31.3% of the total records involved alcohol co-ingestion. Distribution of exposure time was significantly different between deliberate self-poisonings that did and did not involve alcohol ( p ?
机译：目的：调查自杀行为时机的昼夜变化为更好地了解其各种近端风险因素的机会提供了机会。急性使用酒精是一种有效的近端风险因素，但这种风险的性质明白很差。本研究的目的是比较患有涉及酒精与那些涉及酗酒的自我中毒之间的毒药时间变化。方法：在故意自我中毒后，毒理学服务的回顾性分析，1996 - 2016年。进行独立的样品Kolmogorov-Smirnov试验以测试零假设，即毒药摄入时间的日落分布在自主中等具有并且不涉及酒精共同摄取的自我中毒。利用舒加林分析建立了昼夜节律的存在。结果：7467名患者（60.8％的女性）共有11,088名蓄意的自我中毒记录，分析中包括。总之，31.3％的总记录涉及酒精共同摄取。临时自主中毒之间的暴露时间分布显着差异，并且没有涉及酒精（p？<0.001）。酒精共同摄入基团显示出明显更大的尖峰，中毒与晚上以后发生（〜20：00？小时）与未涉及酒精（〜18：00？小时）的中毒相比。结论：本研究根据酒精共摄入的存在，暴露于蓄意的自我中毒中的差分昼夜模式。该分析增加了累积证据，即涉及酒精共同摄取的自杀行为代表着一种不同的亚型，这可能是由社会酒精消费模式驱动的。这也意味着，如果不适合酒精消费，强调药物和酒精服务对酒精相关的自我伤害的重要性，则可能不会发生这种大部分慎重的自我中毒。

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